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Start Over Topic cell receptors Publication Year Range Last 10 years Journal perspectives in psychiatric care Publisher hindawi limited

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1. A pivot from synaptic monoamine processes to further downstream processes: The impact of ketamine research.

Author

Steelman, Brittany Carnley

Subjects
*AFFECTIVE disorders, *ANTIDEPRESSANTS, *CELL receptors, *CELLULAR signal transduction, *KETAMINE, *MEDICAL research, *MONOAMINE oxidase inhibitors, *BRAIN-derived neurotrophic factor, *PHARMACODYNAMICS
Abstract

Purpose: Currently only one‐third of patients treated for depression enjoy complete remission of their negative symptoms. This paper explores ketamine research as it applies to understanding and treating mood illnesses. Conclusions: Ketamine's rapid antidepressant effect implicates downstream signal transduction involving the spontaneous transmissions associated with ketamine's action at the NMDA receptor. Practice Implications: Better understanding of brain neuropathophysiology offers hope for symptom relief to those living with affective illness refractory to currently available medical management. [ABSTRACT FROM AUTHOR]

Published
2019
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