Search

Your search keyword '"Xiaoyang Bi"' showing total 5 results
Start Over Author "Xiaoyang Bi" Journal pest management science
5 results on '"Xiaoyang Bi"'

2. Laboratory bioassay, greenhouse experiment and <scp>3D‐QSAR</scp> studies on berberine analogues: a search for new herbicides based on natural products

Author

Tingfei Zhu, Lijuan Zhou, Sifan Yang, Xiao-Hong Zhang, Ji-Guang Huang, and Xiaoyang Bi

Subjects
0106 biological sciences, Quantitative structure–activity relationship, Berberine, Stereochemistry, Ageratum conyzoides, Quantitative Structure-Activity Relationship, 01 natural sciences, Chloride, chemistry.chemical_compound, medicine, Bioassay, Biological Products, biology, Herbicides, Hydrogen bond, General Medicine, Coptis chinensis, biology.organism_classification, 010602 entomology, chemistry, Insect Science, Biological Assay, Laboratories, Weed, Agronomy and Crop Science, 010606 plant biology & botany, medicine.drug
Abstract

BACKGROUND Berberine is a herbicidal chemical that we isolated from Coptis chinensis. In continuation of our program aimed at discovering and developing natural botanical herbicides, we evaluated the herbicidal activities of 39 berberine analogues and developed a three-dimensional quantitative structure-activity relationship (3D-QSAR) model. RESULTS Among these 39 analogs, the most active compounds were determined to be worenine chloride and coptisine chloride, with median inhibitory concentration (IC50 ) values on all eight tested weed species of

Published
2021

3. Laboratory selection, resistance risk assessment, multi‐resistance, and management of Tetranychus urticae Koch to bifenthrin, bifenazate and cyflumetofen on cowpea

Author

Yaqian Liu, Zhenxiu Liu, Lijuan Zhou, Qiang Yao, Xiaoyang Bi, and Ji-Guang Huang

Subjects
0106 biological sciences, Bifenthrin, Population, Risk Assessment, 01 natural sciences, Toxicology, chemistry.chemical_compound, Pyrethrins, Animals, Bioassay, Tetranychus urticae, Multi resistance, education, Acaricides, education.field_of_study, biology, Acaricide, Vigna, Cyflumetofen, General Medicine, biology.organism_classification, 010602 entomology, Hydrazines, chemistry, Insect Science, Carbamates, PEST analysis, Propionates, Tetranychidae, Agronomy and Crop Science, 010606 plant biology & botany
Abstract

Background Tetranychus urticae (T. urticae) Koch is an important pest of vegetable crops worldwide. In this study, bioassays were carried out to analyze the resistance risk, multi-resistance and management of T. urticae Koch to bifenthrin, bifenazate and cyflumetofen on cowpea. Results The resistance ratios of the adult T. urticae population to bifenthrin (G16), bifenazate (G12) and cyflumetofen (G12) were 31.29, 9.38 and 5.81, respectively. Realized heritability (h 2 ) analysis showed that, under a selection pressure of 50-90% mortality, the generations needed to increase 10-fold LC50 values of bifenthrin, bifenazate and cyflumetofen were 3.64-8.05, 5.75-12.71, and 10.93-24.15, respectively. No obvious multi-resistance among these three acaricides was observed. Synergist bioassay results showed that microsomal multifunctional oxidase (MFO) was involved in bifenthrin resistance of T. urticae, with a synergistic ratio of 22.38. However, MFO and GSTs were not the main factors conferring the resistance to bifenazate. MFO, glutathione S-transferases(GSTs), together with esterase contributed to the development of the resistance to cyflumetofen. Additionally, the toxicity selection index test showed that bifenazate was safe to the natural enemy Neoseiulus barkeri (N. barkeri) with a toxicity selection index (TSI) >484.85, while bifenthrin was the least safe (TSI = 0.92). Conclusions These results demonstrated the T. urticae developed higher resistance risk to bifenthrin compared to bifenazate and cyflumetofen and no obvious multi-resistance among these three acaricides, providing guidance for designing appropriate strategies for the effective application of bifenthrin, bifenazate and cyflumetofen in the field and delaying the development of insecticide resistance. © 2019 Society of Chemical Industry.

Published
2020

4. Cover Image, Volume 76, Issue 5

Author

Zhenxiu Liu, Lijuan Zhou, Qiang Yao, Yaqian Liu, Xiaoyang Bi, and Jiguang Huang

Subjects
Insect Science, General Medicine, Agronomy and Crop Science
Published
2020

5. Laboratory bioassay, greenhouse experiment and 3D-QSAR studies on berberine analogues: a search for new herbicides based on natural products.

Author

Xiaohong Zhang, Tingfei Zhu, Xiaoyang Bi, Sifan Yang, Jiguang Huang, and Lijuan Zhou

Subjects
BERBERINE, NATURAL products, BIOLOGICAL assay, CONTOURS (Cartography), ELECTROSTATIC fields, STRUCTURE-activity relationships, EFFECT of herbicides on plants
Abstract

BACKGROUND: Berberine is a herbicidal chemical that we isolated from Coptis chinensis. In continuation of our program aimed at discovering and developing natural botanical herbicides, we evaluated the herbicidal activities of 39 berberine analogues and developed a three-dimensional quantitative structure–activity relationship (3D-QSAR) model. RESULTS: Among these 39 analogs, the most active compounds were determined to be worenine chloride and coptisine chloride, with median inhibitory concentration (IC50) values on all eight tested weed species of < 10 mg L−1. As a reference, the IC50 values of berberine on six weed species were < 10 mg L−1. Furthermore, the results of a greenhouse experiment showed that at 10 mg L−1, and 7 days after treatment, the effects of worenine chloride and coptisine chloride on Lemna minor and Ageratum conyzoides were significantly higher than those of glyphosate and sulcotrione. In the 3D-QSAR analysis, the electrostatic field contour map indicated that introducing an electropositive group in the N-7, C-9 and C-10 positions would potentially improve the inhibition rate. A positively charged nitrogen atom at the N-7 position was important for activity. Replacement of -OCH3 by -OH at the C-9 and C-10 positions could decrease the inhibitory activity, while the hydrophobic field contour map revealed that the hydrophobicity of the C-10 position was associated with high activity. Moreover, the hydrogen bond acceptor field contour map suggested that the existence of a hydrogen bond acceptor at the C-3 and C-9 positions might affect the inhibition rate. CONCLUSIONS: 3D-QSAR provided meaningful clues to the structural features of berberine analogues that will assist the design of more potent herbicidal compounds in the future. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results