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Formulation and evaluation of floating pulsatile drug delivery system for chronotherapy of hypertension. It is aimed to modulate the pulsatile release profile from time lagged coating using single or a combination of rupturable and erodible polymer. To prepare enalapril maleate core tablets by wet granulation method. To prepare press coated pulsatile tablets by direct compression method. [ABSTRACT FROM AUTHOR]

Asthma is a common chronic inflammatory disease of the airways characterized by variable and recurring symptoms, reversible airflow obstruction and bronchospasm. Asthma is the result of chronic inflammation of the airways which subsequently results in increased contractability of the surrounding smooth muscles. This among other factors leads to bouts of narrowing of the airway. The narrowing is typically reversible with or without treatment. Occasionally the airways themselves change. Common symptoms include wheezing, coughing, chest tightness, and shortness of breath. [ABSTRACT FROM AUTHOR]