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Start Over Author "Palmer, Colin" Journal pharmacogenetics and genomics
10 results on '"Palmer, Colin"'

6. Robust association of the LPA locus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary artery disease outcome during statin treatment

Author

Donnelly, Louise A., primary, van Zuydam, Natalie R., additional, Zhou, Kaixin, additional, Tavendale, Roger, additional, Carr, Fiona, additional, Maitland-van der Zee, Anke H., additional, Leusink, Maarten, additional, de Boer, Anthonius, additional, Doevendans, Pieter A., additional, Asselbergs, Folkert W., additional, Morris, Andrew D., additional, Pearson, Ewan R., additional, Klungel, Olaf H., additional, Doney, Alex S.F., additional, and Palmer, Colin N.A., additional

Published
2013
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9. Robust association of the LPAlocus with low-density lipoprotein cholesterol lowering response to statin treatment in a meta-analysis of 30 467 individuals from both randomized control trials and observational studies and association with coronary artery disease outcome during statin treatment

Author

Donnelly, Louise A., Zuydam, Natalie R. van, Zhou, Kaixin, Tavendale, Roger, Carr, Fiona, Zee, Anke H. Maitland-van der, Leusink, Maarten, de Boer, Anthonius, Doevendans, Pieter A., Asselbergs, Folkert W., Morris, Andrew D., Pearson, Ewan R., Klungel, Olaf H., Doney, Alex S.F., and Palmer, Colin N.A.

Abstract

The LPAsingle-nucleotide polymorphism rs10455872 has been associated with low-density lipoprotein cholesterol (LDLc) lowering response to statins in several randomized control trials (RCTs) and is a known coronary artery disease (CAD) marker. However, it is unclear what residual risk of CAD this marker may have during statin treatment.

Published
2013
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10. Apolipoprotein Egenotypes are associated with lipid-lowering responses to statin treatment in diabetes a Go-DARTS study

Author

Donnelly, Louise A., Palmer, Colin N.A., Whitley, Adrian L., Lang, Chim Choy, Doney, Alex S.F., Morris, Andrew D., and Donnan, Peter T.

Abstract

Apolipoprotein E(APOE) genotypes have been associated with variations in plasma–lipid levels and with response to statins, although the influence of APOEon the response to statins remains controversial, especially in patients with diabetes. We sought to evaluate the association of the APOEgenotype with the low-density lipoprotein cholesterol (LDLc)-lowering response to statins, in a large population-based cohort of patients with diabetes.

Published
2008
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