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Your search keyword '"Süleyman H"' showing total 4 results
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4 results on '"Süleyman H"'

1. Effects of Rumex patientia root extract on indomethacine and ethanol induced gastric damage in rats.

Author

Süleyman H, Demirezer LO, and Kuruüzüm-Uz A

Subjects
Animals, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Cyclooxygenase Inhibitors pharmacology, Isoenzymes metabolism, Male, Plant Extracts pharmacology, Plant Roots chemistry, Prostaglandin-Endoperoxide Synthases metabolism, Rats, Rats, Wistar, Stomach Ulcer chemically induced, Anti-Inflammatory Agents, Non-Steroidal toxicity, Central Nervous System Depressants toxicity, Ethanol toxicity, Indomethacin toxicity, Rumex chemistry, Stomach Ulcer prevention & control
Abstract

The effects of an aqueous root extract from Rumex patientia (D-1) compared to COX-2 selective inhibitors on indomethacine and ethanol induced stomach ulcers were investigated. Adult male Wistar albino rats, weighing between 185-200 g were used. It was determined that D-1 does not show its gastroprotective activity via a COX enzyme in indomethacine induced ulcers. Antioxidant effects protect the gastrointestinal system. The effect of D-1 in ethanol induced ulcers may also be due to its antioxidant effect.

Published
2004

2. Gastroprotective and antiulcerogenic effects of Rumex patientia L. extract.

Author

Süleyman H, Demirezer LO, Kuruüzüm-Uz A, and Akçay F

Subjects
Animals, Anti-Inflammatory Agents, Non-Steroidal, Anti-Ulcer Agents chemistry, Rats, Stomach pathology, Stomach Ulcer chemically induced, Stress, Psychological complications, Turkey, Anti-Ulcer Agents pharmacology, Plants, Medicinal chemistry, Polygonaceae chemistry, Stomach Ulcer drug therapy, Stomach Ulcer prevention & control
Abstract

Gastroprotective and antiulcerogenic effects of the aqueous extract of Rumex patientia L. roots (D-1) were investigated in rats and compared to non-steroidal antiinflammatory drugs (NSAIDs). Whereas oral administration of high doses of NSAIDs caused stomach damage, D-1 (aqueous extract of Rumex patientia roots, 150 and 500 mg/kg) and nimesulid (100 and 300 mg/kg) did not cause any damage. In rats, the number of stress ulcers induced by the administration of 150 mg/kg of D-1 were identical to that of the control group. However, compared to the control group, the number of stress ulcers decreased 1.9 times and the size of ulceration areas decreased 1.1 times in the group treated with 500 mg/kg of D-1.

Published
2002

3. Analgesic and antipyretic activities of Rumex patientia extract on mice and rabbits.

Author

Süleyman H, Demírezer LO, and Kuruüzüm-Uz A

Subjects
Analgesics, Opioid pharmacology, Animals, Aspirin pharmacology, Fever chemically induced, Fever prevention & control, Formaldehyde, Indomethacin pharmacology, Lipopolysaccharides, Male, Mice, Morphine pharmacology, Pain Measurement drug effects, Plant Extracts pharmacology, Plant Roots chemistry, Rabbits, Salmonella typhi chemistry, Analgesics, Non-Narcotic pharmacology, Plants, Medicinal chemistry, Polygonaceae chemistry
Abstract

The aqueous extract from the roots of Rumex patientia L. (Polygonaceae) was investigated for its analgesic and antipyretic effects on mice and rabbits. When the activities of the extract were evaluated in comparison with acetylsalicylic acid (ASA), indomethacin and morphin, it was found to possess significant analgesic and antipyretic activities.

Published
2001

4. Effect of the aqueous extract of Rumex patientia on xylol and hyaluronidase induced capillary permeability compared to indomethacin.

Author

Süleyman H, Demirezer LO, Kuruüzüm A, Büyükokuroğlu ME, Gŏçer F, Banoğlu ZN, and Gepdiremen A

Subjects
Animals, Plant Extracts pharmacology, Rabbits, Capillary Permeability drug effects, Hyaluronoglucosaminidase pharmacology, Plants, Medicinal chemistry, Polygonaceae chemistry, Xylenes pharmacology
Abstract

In this study, the effect of an aqueous extract of Rumex patientia L. (Polygonaceae) (D-1) on capillary permeability which was induced by xylol and hyaluronidase was investigated. Experiments were conducted on rabbits according to Monakova and Matusis methods. The effects of D-1 were compared to those of indomethacin, which was used as a control throughout the experiment. Both D-1 (100 mg/kg) and indomethacin (10 mg/kg) were administered orally. As a result, D-1 inhibited capillary permeability, which was induced by xylol and hyaluronidase, and it was found that it was as effective as indomethacin.

Published
2001

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