1. New Chiral Ortho-P,S-Difunctionalized Aromatic Compounds.
- Author
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Abrunhosa, Isabelle, Drabowicz, Jozef, Grach, Guillaume, Gulea, Mihaela, Hamel, Matthieu, Masson, Serge, Mikolajczyk, Marian, and Vazeux, Michel
- Subjects
AROMATIC compounds ,ORGANIC cyclic compounds ,THIOLS ,ENANTIOMERS ,CHIRALITY ,CHEMISTRY - Abstract
A new method to prepare enantioenriched sulfinates was developed to obtain optically active ortho-methylsulfinyl(phenylphosphonates). It consists of a diastereoselective oxidation of sulfenates to sulfinates. Additionally, preliminary results concerning the synthesis of ortho-phophonylated benzylic thiol derivatives via a new P-S to P-C [1,4]-rearrangement and a first synthetic application of these compounds are also described. [ABSTRACT FROM AUTHOR]
- Published
- 2005
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