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Cascading failure in interdependent networks is studied in recent decade, and considerable research has been done on systems modeling, vulnerability analysis and protection strategy, but partial work on vulnerability analysis and protection strategy still cannot completely utilize coupling relation between physical power grid and communication network into research, thus we introduce inter-relation of support nodes to perfect the strategies. Compared with traditional vulnerability analysis, we, through studying state of systems after attack, analyze robustness of systems. From the perspective of attacker, four attack strategies considering inter-relation have been proposed, and simulation results verify the serious destructiveness of attack strategies to steady of systems. Taking inter-relation and heterogeneity of networks into consideration, we propose two redundancy protection strategies on intra-links redundancy. Both protection strategies are proved to attain better performance than other strategies without considering inter-relation, meanwhile existence of saturation point can give guidance on rational allocation of limited intra-links. • Four optimizing attack strategies are proposed to detect critical nodes. • Cascading failure is simulated in four coupled symmetric networks. • Two optimizing intra-links addition strategies are raised. • The effectiveness of optimizing attack and intra-links addition strategies. • Discovery of saturation point has guide in rationally allocating limited resource. [ABSTRACT FROM AUTHOR]