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9 results on '"Che, Yi"'

2. Three new isopimaric acid diterpenoids from the bark of Cryptomeria japonica and their xanthine oxidase inhibitory activity

Author

Che-Yi Chao, Sheng-Yang Wang, Jih Jung Chen, Chi-I Chang, Cheng-Chi Chen, Chiy-Rong Chen, and Yueh-Hsiung Kuo

Subjects
biology, Chemistry, Cryptomeria, Plant Science, biology.organism_classification, Inhibitory postsynaptic potential, Biochemistry, Japonica, Xanthine oxidase activity, chemistry.chemical_compound, visual_art, visual_art.visual_art_medium, Isopimaric acid, Bark, Spectral data, Xanthine oxidase, Agronomy and Crop Science, Biotechnology
Abstract

Three new isopimaric acid diterpenoids, 6-oxoisopimaric acid (1), 6α-hydroxyisopimaric acid (2), and isopimara-7,9(11),15-trien-18-oic acid (4), together with two known isopimaric acid diterpenoids, isopimaric acid (3), and 8(14),15-isopimaradien-18-oic acid (5), were isolated from the bark of Cryptomeria japonica D. Don. Their structures were determined by analysis of spectroscopic data and comparison with the spectral data of known analogues. At the concentration of 50 μM, compounds 1–5 inhibited xanthine oxidase activity by 17.3, 16.5, 2.6, 30.5, and 24.5 %, respectively.

Published
2021

4. New 7-oxoabietane-type diterpenoids from the bark of Cryptomeria japonica and their xanthine oxidase inhibitory activity

Author

Bang-Jau You, Yueh-Hsiung Kuo, Sheng-Yang Wang, Che-Yi Chao, Cheng-Chi Chen, Tzong-Huei Lee, Yi-Jen Li, Ming-Jen Cheng, and Chi-I Chang

Subjects
biology, 010405 organic chemistry, Chemistry, Stereochemistry, Cryptomeria, Ether, Plant Science, Inhibitory postsynaptic potential, biology.organism_classification, 01 natural sciences, Biochemistry, Japonica, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, visual_art, visual_art.visual_art_medium, Bark, Xanthine oxidase, Agronomy and Crop Science, Biotechnology
Abstract

Three new 7-oxoabietane-type diterpenoids, 3-oxosugiol methyl ether (1), 18-hydroxysugiol (2), and 1β-hydroxysugiol (3), as well as two known 7-oxoabietane-type diterpenoids, 6α-hydroxysugiol (4) and 6α-acetoxysugiol (5), were isolated from the bark of Cryptomeria japonica D. Don. Their structures were elucidated mainly by NMR and HREIMS, as well as on comparison with the data of known analogues. At the concentration of 75 μM, compounds 2 and 5 exhibited 11.9 and 21.7% xanthine oxidase inhibitory activity, respectively.

Published
2018

6. Two new flavonoids from Derris laxiflora Benth

Author

Chun-Ching Shih, Shih-Chang Chien, Louis Kuoping Chao, Jyh-Horng Wu, His-Lin Chiu, Yueh-Hsiung Kuo, Che-Yi Chao, Sheng-Yang Wang, and Chien-Chih Chen

Subjects
Derris laxiflora, 010405 organic chemistry, Chemistry, Chemical structure, Plant composition, Plant Science, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Botany, Agronomy and Crop Science, Chemical composition, Biotechnology
Abstract

Two new compounds, derriscoumaronochromone ( 1 ) and cis -3,4′-dihydroxy- 5,7-dimethoxyflavan ( 2 ), as well as trans -4'- O -methylcatechin ( 3 ) were isolated from Derris laxiflora , The structures of these compounds were determined by analysis of their spectroscopic data.

Published
2017

8. Two new labdane-type diterpenes from the wood of Cunninghamia konishii

Author

Wei-Yi Cheng, Minoru Tsuzuki, Yen-Cheng Li, Chi-I Chang, Che-Yi Chao, Ching-jang Huang, Sakae Amagaya, Yueh-Hsiung Kuo, and Yong-Han Hong

Subjects
biology, Traditional medicine, Sclareol, Stereochemistry, Plant Science, biology.organism_classification, Biochemistry, Terpenoid, Labdane, chemistry.chemical_compound, chemistry, Phytochemical, Methanol, Cunninghamia, Agronomy and Crop Science, Taxodiaceae, Biotechnology
Abstract

Our preliminary pharmaceutical screening revealed that the methanol extract of wood of Cunninghamia konishii possessed significant anti-inflammatory activity. Further phytochemical investigation led to the isolation of two new labdane-type diterpenoids, (12S,13S)-12,13-epoxy-8(17),14-labdadien-18-ol (1) and (12S,13S)-12,13-epoxy-8(17),14-labdadien-19-oic acid (2), along with four known labdane-type diterpenoids, (12R,13R)-12,13-epoxy-labda-8(17),14-dien-19-oic acid (3), 12,13-dihydroxylabda-8(17),14-dien-19-oic acid (4), sclareol (5), and 13-epi-sclareol (6). Their structures were determined by analysis of spectroscopic data and comparison with the data of known analogues.

Published
2014

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