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Your search keyword '"Cheng-qi Xiong"' showing total 6 results
Start Over Author "Cheng-qi Xiong" Journal planta medica
6 results on '"Cheng-qi Xiong"'

1. Spirostanol Saponins Derivated from the Seeds ofTrigonella foenum-graecumbyβ-Glucosidase Hydrolysis and Their Inhibitory Effects on Rat Platelet Aggregation

Author

Bai-Ping Ma, Bing Feng, Bin Liu, Yang Zhao, Yue Cong, He-Shui Yu, Xu Pang, Bing-Xing Han, Yuwen Cong, Wei Song, Da-Wei Tan, Cheng-Qi Xiong, and Li-Ping Kang

Subjects
Male, Trigonella, Platelet Aggregation, Platelet aggregation, Saponin, Pharmaceutical Science, Inhibitory postsynaptic potential, Analytical Chemistry, Hydrolysis, Enzymatic hydrolysis, Drug Discovery, Spirostans, Animals, Rats, Wistar, β glucosidase, Pharmacology, chemistry.chemical_classification, Chromatography, Molecular Structure, biology, Plant Extracts, Chemistry, beta-Glucosidase, Organic Chemistry, Saponins, Furostanol saponin, biology.organism_classification, Rats, Complementary and alternative medicine, Seeds, Molecular Medicine, Drugs, Chinese Herbal
Abstract

Nine spirostanol saponins (1-9) and seven mixtures of 25 R and 25 S spirostanol saponin isomers (10-16) were obtained from the seeds of Trigonella foenum-graecum after enzymatic hydrolysis of the furostanol saponin fraction by β-glucosidase. Their structures were determined by NMR and MS spectroscopy. Among them, 1- 4, 6, 8, and 9 were new compounds and five, 11B, 12A, 13B, 14A, and 14B, were new structures observed from seven mixtures. In addition, the inhibitory effects of all saponins on rat platelet aggregation were evaluated.

Published
2011

2. Natural products biotransformation and its application

Author

M Zhao, Bing Feng, L Lu, Wen-bin Zhou, Jie Zhang, He-Shui Yu, Hong-zhi Huang, M Cao, Cheng-Qi Xiong, Yang Zhao, and Bai-Ping Ma

Subjects
Pharmacology, Complementary and alternative medicine, Biotransformation, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Organic chemistry, Natural (archaeology), Analytical Chemistry
Published
2012

3. Steroidal glycosides from the rhizomes of Anemarrhena asphodeloides and their antiplatelet aggregation activity

Author

Bin Li, Yue Cong, Chao Liu, Bai-Ping Ma, Yang Zhao, Jie Zhang, Zu-Yin Yu, Li-Ping Kang, Da-Wei Tan, Cheng-Qi Xiong, He-Shui Yu, and Yuwen Cong

Subjects
Male, Magnetic Resonance Spectroscopy, Platelet aggregation, Steroidal glycosides, Platelet Aggregation, Stereochemistry, Pharmaceutical Science, Analytical Chemistry, chemistry.chemical_compound, Anemarrhena asphodeloides, Drug Discovery, Animals, Glycosides, Rats, Wistar, Inhibitory effect, Pharmacology, Anemarrhena, Plants, Medicinal, biology, Molecular Structure, Liliaceae, Organic Chemistry, Saponins, biology.organism_classification, Rhizome, Rats, Adenosine Diphosphate, Adenosine diphosphate, Complementary and alternative medicine, chemistry, Molecular Medicine, Timosaponin J, Steroids, Platelet Aggregation Inhibitors, Drugs, Chinese Herbal
Abstract

Five new steroidal glycosides, timosaponin J ( 1), timosaponin K ( 2), (25 S)-karatavioside C ( 5), timosaponin L ( 6), and (25 S)-officinalisnin-I ( 8), together with eight known steroidal saponins, timosaponin E (1) ( 3), purpureagitosid ( 4), timosaponin BII ( 7), timosaponin B III ( 9), anemarrhenasaponin I ( 10), anemarrhenasaponin III ( 11), anemarrhenasaponin A (2) ( 12), and timosaponin A III ( 13), were isolated from the rhizomes of Anemarrhena asphodeloides. Their structures were elucidated on the basis of spectroscopic and chemical evidence. The aglycones of compounds 1 and 2 are new aglycones. Compounds 1- 13 were evaluated for their platelet aggregation activities, and compound 13 exhibited the strongest inhibitory effect on adenosine diphosphate (ADP)-induced platelet aggregation.

Published
2012

4. Steroidal Saponins from the Seeds of Chinese Trigonella foenum-graecum L

Author

Bing Feng, Bai-Ping Ma, Li-Ping Kang, He-Shui Yu, Xu Pang, Yang Zhao, Da-Wei Tan, and Cheng-Qi Xiong

Subjects
Pharmacology, Trigonella, Traditional medicine, biology, business.industry, Organic Chemistry, Pharmaceutical Science, biology.organism_classification, Analytical Chemistry, Complementary and alternative medicine, Drug Discovery, Molecular Medicine, Medicine, business
Published
2011

5. Steroidal Glycosides from the Rhizomes of Anemarrhena asphodeloides and Their Antiplatelet Aggregation Activity.

Author

Li-ping Kang, Jie Zhang, Yue Cong, Bin Li, Cheng-qi Xiong, Yang Zhao, Da-wei Tan, He-shui Yu, Zu-yin Yu, Yu-wen Cong, Chao Liu, and Bai-ping Ma

Subjects
ANIMAL experimentation, BIOLOGICAL assay, GLYCOSIDES, HIGH performance liquid chromatography, MASS spectrometry, MICE, MOLECULAR structure, PHARMACEUTICAL chemistry, PLANT stems, PLATELET aggregation inhibitors, DESCRIPTIVE statistics, MAGNETIC resonance angiography
Abstract

Five new steroidal glycosides, timosaponin J (1), timosaponin K (2), (25S)-karatavioside C (5), timosaponin L (6), and (25S)-officinalisnin-I (8), together with eight known steroidal saponins, timosaponin E1 (3), purpureagitosid (4), timosaponin BII (7), timosaponin B III (9), anemarrhenasaponin I (10), anemarrhenasaponin III (11), anemarrhenasaponin A2 (12), and timosaponin A III (13), were isolated from the rhizomes of Anemarrhena asphodeloides. Their structures were elucidated on the basis of spectroscopic and chemical evidence. The aglycones of compounds 1 and 2 are new aglycones. Compounds 1-13 were evaluated for their platelet aggregation activities, and compound 13 exhibited the strongest inhibitory effect on adenosine diphosphate (ADP)-induced platelet aggregation. [ABSTRACT FROM AUTHOR]

Published
2012
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