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International audience; In continuation of our studies on Algerian Apiaceous plants [1] we report here a phytochemical study of aerial parts of Bupleurum montanum, an Algerian endemic species [2], collected from Megress Mountain (Eastern Algeria) at 1500m above sea level, during June 2006. Quercitin 1 [3] and tamarixetin 2 [4] were isolated from the ethylacetate extract. Isorhamnetin-3-rutinoside 3 [5], originally isolated from the flowers of Narcissus tazetta [6], and kaempferol-3-rutinoside 4 [4] were obtained from the n-butanol extract. The structural elucidation was performed mainly by MS, 1D and 2D NMR spectrum data.

Eleven phenolic Compounds have been isolated from the ethanolic extract of SELAGINELLA DOEDERLEINII by a combination of Chromatographic techniques. These are five lignans: (-)-lirioresinol A, (-)-lirioresinol B, (+)-wikstromol, (-)-nortracheloside, (+)-matairesinol ( 1), two phenylpropanones: 3-hydroxy-1-(3-methoxy-4-hydroxyphenyl)-propan-1-one ( 2), 3-hydroxy-1-(3,5 -dimethoxy-4-hydroxyphenyl)-propan-1-one ( 3), and four biflavonoids: amentoflavone, 7,7''-di- O-methylamentoflavone, 7,4',7'',4'''-tetra- O-methylamentoflavone, and heveaflavone ( 4). Compounds 1, 2, and 3 are novel natural secondary metabolites. Their structures were deduced from their spectral data (mainly (1)H-NMR, mass, and CD). Lignans are described here for the first time in the family Selaginellaceae. Their cytotoxic activity against L 929 murine cells accounts for the use of the plant in traditional Chinese medicine as an anticancer agent.