1. Linkage to care and treatment for TB and HIV among people newly diagnosed with TB or HIV-associated TB at a large, inner city South African hospital.
- Author
-
Voss De Lima Y, Evans D, Page-Shipp L, Barnard A, Sanne I, Menezes CN, and Van Rie A
- Subjects
- Adult, Demography, Female, HIV Infections epidemiology, Humans, Male, Referral and Consultation, Risk Factors, South Africa epidemiology, Treatment Outcome, Tuberculosis complications, Tuberculosis epidemiology, HIV Infections complications, HIV Infections drug therapy, Hospitals, Urban statistics & numerical data, Patient Care statistics & numerical data, Tuberculosis diagnosis, Tuberculosis drug therapy
- Abstract
Objective: To assess the outcomes of linkage to TB and HIV care and identify risk factors for poor referral outcomes., Design: Cohort study of TB patients diagnosed at an urban hospital., Methods: Linkage to care was determined by review of clinic files, national death register, and telephone contact, and classified as linked to care, delayed linkage to care (>7 days for TB treatment, >30 days for HIV care), or failed linkage to care. We performed log-binomial regression to identify patient and referral characteristics associated with poor referral outcomes., Results: Among 593 TB patients, 23% failed linkage to TB treatment and 30.3% of the 77.0% who linked to care arrived late. Among 486 (86.9%) HIV-infected TB patients, 38.3% failed linkage to HIV care, and 32% of the 61.7% who linked to care presented late. One in six HIV-infected patients failed linkage to both TB and HIV care. Only 20.2% of HIV-infected patients were referred to a single clinic for integrated care. A referral letter was present in 90.3%, but only 23.7% included HIV status and 18.8% CD4 cell count. Lack of education (RR 1.85) and low CD4 count (CD4≤50 vs. >250cells/mm(3); RR 1.66) were associated with failed linkage to TB care. Risk factors for failed linkage to HIV care were antiretroviral-naïve status (RR 1.29), and absence of referral letter with HIV or CD4 cell count (RR1.23)., Conclusions: Linkage to TB/HIV care should be strengthened by communication of HIV and CD4 results, ART initiation during hospitalization and TB/HIV integration at primary care.
- Published
- 2013
- Full Text
- View/download PDF