Search

Your search keyword '"Cuevas, Luis E."' showing total 13 results
Start Over Author "Cuevas, Luis E." Journal plos one
13 results on '"Cuevas, Luis E."'

1. Pooling samples to increase testing capacity with Xpert Xpress SARS-CoV-2 during the Covid-19 pandemic in Lao People’s Democratic Republic

Author

Iem, Vibol, primary, Xangsayarath, Phonepadith, additional, Chittamany, Phonenaly, additional, Suthepmany, Sakhone, additional, Siphanthong, Souvimone, additional, Paboriboune, Phimpha, additional, Somphavong, Silaphet, additional, Konstantina, Kontogianni, additional, Khan, Jahangir A. M., additional, Edwards, Thomas, additional, Wingfield, Tom, additional, Creswell, Jacob, additional, Dominguez, Jose, additional, and Cuevas, Luis E., additional

Published
2022
Full Text
View/download PDF

2. A prospective diagnostic evaluation of accuracy of self-taken and healthcare worker-taken swabs for rapid COVID-19 testing.

Author

Savage, Helen R., Finch, Lorna, Body, Richard, Watkins, Rachel L., Hayward, Gail, Cook, Eloïse, Cubas-Atienzar, Ana I., Cuevas, Luis E., MacPherson, Peter, and Adams, Emily R.

Subjects
MEDICAL personnel, COVID-19 testing, POINT-of-care testing, DIAGNOSIS methods, MEDICAL care
Abstract

Background: Rapid diagnostic tests (RDTs) developed for point of care detection of SARS-CoV-2 antigen are recommended by WHO to use trained health care workers to collect samples. We hypothesised that self-taken samples are non-inferior for use with RDTs to diagnose COVID-19. We designed a prospective diagnostic evaluation comparing self-taken and healthcare worker (HCW)-taken throat/nasal swabs to perform RDTs for SARS-CoV-2, and how these compare to RT-PCR. Methods: Eligible participants 18 years or older with symptoms of COVID-19. 250 participants recruited at the NHS Test and Trace drive-through community PCR testing site (Liverpool, UK); one withdrew before analysis. Self-administered throat/nasal swab for the Covios® RDT, a trained HCW taken throat/nasal sample for PCR and HCW comparison throat/nasal swab for RDT were collected. RDT results were compared to RT-PCR, as the reference standard, to calculate sensitivity and specificity. Findings: Seventy-five participants (75/249, 30.1%) were positive by RT-PCR. RDTs with self-taken swabs had a sensitivity of 90.5% (67/74, 95% CI: 83.9–97.2), compared to 78.4% (58/74, 95% CI: 69.0–87.8) for HCW-taken swabs (absolute difference 12.2%, 95% CI: 4.7–19.6, p = 0.003). Specificity for self-taken swabs was 99.4% (173/174, 95% CI: 98.3–100.0), versus 98.9% (172/174, 95% CI: 97.3–100.0) for HCW-taken swabs (absolute difference 0.6%, 95% CI: 0.5–1.7, p = 0.317). The PPV of self-taken RDTs (98.5%, 67/68, 95% CI: 95.7–100.0) and HCW-taken RDTs (96.7%, 58/60, 95% CI 92.1–100.0) were not significantly different (p = 0.262). However, the NPV of self-taken swab RDTs was significantly higher (96.1%, 173/180, 95% CI: 93.2–98.9) than HCW-taken RDTs (91.5%, 172/188, 95% CI 87.5–95.5, p = 0.003). Interpretation: In conclusion, self-taken swabs for COVID-19 testing offer an accurate alternative to healthcare worker taken swabs for use with RDTs. Our results demonstrate that, with no training, self-taken throat/nasal samples can be used by lay individuals as part of rapid testing programmes for symptomatic adults. This is especially important where the lack of trained healthcare workers restricts access to testing. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

4. Cytokine Kinetics in the First Week of Tuberculosis Therapy as a Tool to Confirm a Clinical Diagnosis and Guide Therapy

Author

den Hertog, Alice L., primary, Montero-Martín, María, additional, Saunders, Rachel L., additional, Blakiston, Matthew, additional, Menting, Sandra, additional, Sherchand, Jeevan B., additional, Lawson, Lovett, additional, Oladimeji, Olanrewaju, additional, Abdurrahman, Saddiq T., additional, Cuevas, Luis E., additional, and Anthony, Richard M., additional

Published
2015
Full Text
View/download PDF

5. Incidence of Rotavirus and Circulating Genotypes in Northeast Brazil during 7 Years of National Rotavirus Vaccination

Author

Gurgel, Ricardo Q., primary, Alvarez, Alberto De Juan, additional, Rodrigues, Alda, additional, Ribeiro, Robergson R., additional, Dolabella, Sílvio S., additional, Da Mota, Natanael L., additional, Santos, Victor S., additional, Iturriza-Gomara, Miren, additional, Cunliffe, Nigel A., additional, and Cuevas, Luis E., additional

Published
2014
Full Text
View/download PDF

7. Intensive-Phase Treatment Outcomes among Hospitalized Multidrug-Resistant Tuberculosis Patients: Results from a Nationwide Cohort in Nigeria

Author

Oladimeji, Olanrewaju, primary, Isaakidis, Petros, additional, Obasanya, Olusegun J., additional, Eltayeb, Osman, additional, Khogali, Mohammed, additional, Van den Bergh, Rafael, additional, Kumar, Ajay M. V., additional, Hinderaker, Sven Gudmund, additional, Abdurrahman, Saddiq T., additional, Lawson, Lovett, additional, and Cuevas, Luis E., additional

Published
2014
Full Text
View/download PDF

8. Innovative Community-Based Approaches Doubled Tuberculosis Case Notification and Improve Treatment Outcome in Southern Ethiopia

Author

Yassin, Mohammed A., primary, Datiko, Daniel G., additional, Tulloch, Olivia, additional, Markos, Paulos, additional, Aschalew, Melkamsew, additional, Shargie, Estifanos B., additional, Dangisso, Mesay H., additional, Komatsu, Ryuichi, additional, Sahu, Suvanand, additional, Blok, Lucie, additional, Cuevas, Luis E., additional, and Theobald, Sally, additional

Published
2013
Full Text
View/download PDF

9. A Molecular Epidemiological and Genetic Diversity Study of Tuberculosis in Ibadan, Nnewi and Abuja, Nigeria

Author

Lawson, Lovett, primary, Zhang, Jian, additional, Gomgnimbou, Michel K., additional, Abdurrahman, Saddiq T., additional, Le Moullec, Stéphanie, additional, Mohamed, Fatima, additional, Uzoewulu, Gertrude N., additional, Sogaolu, Olumide M., additional, Goh, Khye Seng, additional, Emenyonu, Nnamdi, additional, Refrégier, Guislaine, additional, Cuevas, Luis E., additional, and Sola, Christophe, additional

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results