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1. Post-exercise high-sensitivity troponin T levels in patients with suspected unstable angina.

Author

Gaetano Antonio Lanza, Erica Mencarelli, Veronica Melita, Antonio Tota, Maurizio Gabrielli, Filippo Sarullo, Chiara Cordischi, Annalisa Potenza, Silvia Cardone, Antonio De Vita, Antonio Bisignani, Laura Manfredonia, Giuseppa Caccamo, Giuseppe Vitale, Silvia Baroni, Mirca Antenucci, Filippo Crea, and Francesco Franceschi

Subjects
Medicine, Science
Abstract

BACKGROUND:Previous studies showed that troponin blood levels may increase after exercise. In this study we assessed whether, among patients admitted with suspected unstable angina, the increase in high-sensitive troponin T (hs-TnT) levels after exercise stress test (EST) might help identify those with obstructive coronary artery disease (CAD) and predict symptom recurrence during short term follow-up. METHODS:Maximal treadmill EST was performed in 69 consecutive patients admitted to the emergency room with a suspicion of unstable angina (acute chest pain but confirmed normal serum levels of cardiac troponins) was measured before and 4 hours after EST. Coronary angiography was performed in 22 patients (32.8%). RESULTS:hs-TnT increased after EST compared to baseline in the whole population (from 0.84±0.65 to 1.17±0.87 ng/dL, p

Published
2019
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2. Post-exercise high-sensitivity troponin T levels in patients with suspected unstable angina

Author

Mirca Antenucci, Filippo Crea, Gaetano Antonio Lanza, Giuseppe Vitale, L Manfredonia, Francesco Franceschi, Annalisa Potenza, Antonio De Vita, Silvia Baroni, Chiara Cordischi, Antonio Tota, Filippo M. Sarullo, Silvia Cardone, Erica Mencarelli, Giuseppa Caccamo, Antonio Bisignani, Veronica Melita, and Maurizio Gabrielli

Subjects
Male, Cardiovascular Procedures, Coronary Artery Disease, 030204 cardiovascular system & hematology, Cardiovascular Medicine, Chest pain, Coronary Angiography, Biochemistry, Vascular Medicine, Diagnostic Radiology, Angina, Coronary artery disease, Electrocardiography, 0302 clinical medicine, Endocrinology, Ischemia, Medicine and Health Sciences, Coronary Heart Disease, Cardiovascular Imaging, education.field_of_study, Multidisciplinary, Troponin T, biology, Radiology and Imaging, Angiography, Middle Aged, musculoskeletal system, Troponin, Bioassays and Physiological Analysis, N/A, Cardiology, Medicine, Female, medicine.symptom, Research Article, medicine.medical_specialty, Imaging Techniques, Endocrine Disorders, Science, Population, Surgical and Invasive Medical Procedures, Research and Analysis Methods, 03 medical and health sciences, Diagnostic Medicine, Internal medicine, Heart rate, medicine, Diabetes Mellitus, Humans, Angina, Unstable, education, Exercise, Aged, business.industry, Unstable angina, Settore MED/09 - MEDICINA INTERNA, Electrophysiological Techniques, Angioplasty, Biology and Life Sciences, Proteins, 030229 sport sciences, medicine.disease, Cytoskeletal Proteins, Metabolic Disorders, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, biology.protein, Exercise Test, Cardiac Electrophysiology, business, Coronary Angioplasty, Biomarkers
Abstract

Background Previous studies showed that troponin blood levels may increase after exercise. In this study we assessed whether, among patients admitted with suspected unstable angina, the increase in high-sensitive troponin T (hs-TnT) levels after exercise stress test (EST) might help identify those with obstructive coronary artery disease (CAD) and predict symptom recurrence during short term follow-up. Methods Maximal treadmill EST was performed in 69 consecutive patients admitted to the emergency room with a suspicion of unstable angina (acute chest pain but confirmed normal serum levels of cardiac troponins) was measured before and 4 hours after EST. Coronary angiography was performed in 22 patients (32.8%). Results hs-TnT increased after EST compared to baseline in the whole population (from 0.84±0.65 to 1.17±0.87 ng/dL, p

Published
2019

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