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8 results on '"Ikuta, Kazuyoshi"'

3. Emerging Antigenic Variants at the Antigenic Site Sb in Pandemic A(H1N1)2009 Influenza Virus in Japan Detected by a Human Monoclonal Antibody

Author

Yasugi, Mayo, primary, Kubota-Koketsu, Ritsuko, additional, Yamashita, Akifumi, additional, Kawashita, Norihito, additional, Du, Anariwa, additional, Misaki, Ryo, additional, Kuhara, Motoki, additional, Boonsathorn, Naphatsawan, additional, Fujiyama, Kazuhito, additional, Okuno, Yoshinobu, additional, Nakaya, Takaaki, additional, and Ikuta, Kazuyoshi, additional

Published
2013
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4. Reliability of a Newly-Developed Immunochromatography Diagnostic Kit for Pandemic Influenza A/H1N1pdm Virus: Implications for Drug Administration

Author

Sasaki, Tadahiro, primary, Kubota-Koketsu, Ritsuko, additional, Takei, Michihiro, additional, Hagihara, Tatsuo, additional, Iwamoto, Shinichi, additional, Murao, Takuya, additional, Sawami, Kazuo, additional, Fukae, Daizou, additional, Nakamura, Masahiro, additional, Nagata, Eiichi, additional, Kawakami, Akira, additional, Mitsubayashi, Yuko, additional, Ohno, Masafumi, additional, Uehara, Yasuo, additional, Fukukawa, Takashi, additional, Kanai, Yuta, additional, Kosaka, Mieko, additional, and Ikuta, Kazuyoshi, additional

Published
2012
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5. Frequency of D222G and Q223R Hemagglutinin Mutants of Pandemic (H1N1) 2009 Influenza Virus in Japan between 2009 and 2010

Author

Yasugi, Mayo, primary, Nakamura, Shota, additional, Daidoji, Tomo, additional, Kawashita, Norihito, additional, Ramadhany, Ririn, additional, Yang, Cheng-Song, additional, Yasunaga, Teruo, additional, Iida, Tetsuya, additional, Horii, Toshihiro, additional, Ikuta, Kazuyoshi, additional, Takahashi, Kazuo, additional, and Nakaya, Takaaki, additional

Published
2012
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6. Molecular Evolution of HIV-1 CRF01_AE Env in Thai Patients

Author

Boonchawalit, Samatchaya, primary, Jullaksorn, Duangrat, additional, Uttiyoung, Jiraporn, additional, Yowang, Amara, additional, Krathong, Nongkran, additional, Chautrakul, Sununta, additional, Yamashita, Akifumi, additional, Ikuta, Kazuyoshi, additional, Roobsoong, Amornsak, additional, Kanitvittaya, Sangkom, additional, Sawanpanyalert, Pathom, additional, and Kameoka, Masanori, additional

Published
2011
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7. Direct Metagenomic Detection of Viral Pathogens in Nasal and Fecal Specimens Using an Unbiased High-Throughput Sequencing Approach

Author

Nakamura, Shota, primary, Yang, Cheng-Song, additional, Sakon, Naomi, additional, Ueda, Mayo, additional, Tougan, Takahiro, additional, Yamashita, Akifumi, additional, Goto, Naohisa, additional, Takahashi, Kazuo, additional, Yasunaga, Teruo, additional, Ikuta, Kazuyoshi, additional, Mizutani, Tetsuya, additional, Okamoto, Yoshiko, additional, Tagami, Michihira, additional, Morita, Ryoji, additional, Maeda, Norihiro, additional, Kawai, Jun, additional, Hayashizaki, Yoshihide, additional, Nagai, Yoshiyuki, additional, Horii, Toshihiro, additional, Iida, Tetsuya, additional, and Nakaya, Takaaki, additional

Published
2009
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8. Molecular Characterization of Clostridium botulinum Isolates from Foodborne Outbreaks in Thailand, 2010.

Author

Wangroongsarb, Piyada, Kohda, Tomoko, Jittaprasartsin, Chutima, Suthivarakom, Karun, Kamthalang, Thanitchi, Umeda, Kaoru, Sawanpanyalert, Pathom, Kozaki, Shunji, and Ikuta, Kazuyoshi

Subjects
CLOSTRIDIUM botulinum, MOLECULAR biology, FOODBORNE diseases, ETIOLOGY of diseases, NEUROTOXIC agents, LABORATORY mice
Abstract

Background: Thailand has had several foodborne outbreaks of botulism, one of the biggest being in 2006 when laboratory investigations identified the etiologic agent as Clostridium botulinum type A. Identification of the etiologic agent from outbreak samples is laborious using conventional microbiological methods and the neurotoxin mouse bioassay. Advances in molecular techniques have added enormous information regarding the etiology of outbreaks and characterization of isolates. We applied these methods in three outbreaks of botulism in Thailand in 2010. Methodology/Principal Findings: A total of 19 cases were involved (seven each in Lampang and Saraburi and five in Maehongson provinces). The first outbreak in Lampang province in April 2010 was associated with C. botulinum type F, which was detected by conventional methods. Outbreaks in Saraburi and Maehongson provinces occurred in May and December were due to C. botulinum type A1(B) and B that were identified by conventional methods and molecular techniques, respectively. The result of phylogenetic sequence analysis showed that C. botulinum type A1(B) strain Saraburi 2010 was close to strain Iwate 2007. Molecular analysis of the third outbreak in Maehongson province showed C. botulinum type B8, which was different from B1–B7 subtype. The nontoxic component genes of strain Maehongson 2010 revealed that ha33, ha17 and botR genes were close to strain Okra (B1) while ha70 and ntnh genes were close to strain 111 (B2). Conclusion/Significance: This study demonstrates the utility of molecular genotyping of C. botulinum and how it contributes to our understanding the epidemiology and variation of boNT gene. Thus, the recent botulism outbreaks in Thailand were induced by various C. botulinum types. [ABSTRACT FROM AUTHOR]

Published
2014
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