1. Impact of uncertainties in exposure assessment on estimates of thyroid cancer risk among Ukrainian children and adolescents exposed from the Chernobyl accident.
- Author
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Little, Mark, Kukush, Alexander, Masiuk, Sergii, Shklyar, Sergiy, Carroll, Raymond, Lubin, Jay, Kwon, Deukwoo, Brenner, Alina, Tronko, Mykola, Mabuchi, Kiyohiko, Bogdanova, Tetiana, Hatch, Maureen, Tereshchenko, Valeriy, Ostroumova, Evgenia, Bouville, André, Drozdovitch, Vladimir, Chepurny, Mykola, Kovgan, Lina, Simon, Steven, Shpak, Victor, Likhtarev, Ilya, and Zablotska, Lydia
- Subjects
Adolescent ,Chernobyl Nuclear Accident ,Child ,Child ,Preschool ,Dose-Response Relationship ,Radiation ,Environmental Exposure ,Female ,Humans ,Incidence ,Infant ,Infant ,Newborn ,Iodine Radioisotopes ,Likelihood Functions ,Male ,Monte Carlo Method ,Neoplasms ,Radiation-Induced ,Odds Ratio ,Radiometry ,Risk Factors ,Thyroid Gland ,Thyroid Neoplasms ,Ukraine ,Uncertainty - Abstract
The 1986 accident at the Chernobyl nuclear power plant remains the most serious nuclear accident in history, and excess thyroid cancers, particularly among those exposed to releases of iodine-131 remain the best-documented sequelae. Failure to take dose-measurement error into account can lead to bias in assessments of dose-response slope. Although risks in the Ukrainian-US thyroid screening study have been previously evaluated, errors in dose assessments have not been addressed hitherto. Dose-response patterns were examined in a thyroid screening prevalence cohort of 13,127 persons aged
- Published
- 2014