1. Randomized controlled trial of early, small-volume formula supplementation among newborns: A study protocol
- Author
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Ginsburg, Amy Sarah, de, Augusto Braima, Nankabirwa, Victoria, Co, Raimundo, Murungi, Joanitta, Kim, Mi-Ok, Brim, Rachel, Namiiro, Flavia, Namugga, Olive, Hartigan-O’Connor, Dennis J, Roberts, Susan B, and Flaherman, Valerie
- Subjects
Paediatrics ,Biomedical and Clinical Sciences ,Nutrition and Dietetics ,Breastfeeding ,Lactation and Breast Milk ,Preterm ,Low Birth Weight and Health of the Newborn ,Prevention ,Clinical Research ,Pediatric ,Clinical Trials and Supportive Activities ,Perinatal Period - Conditions Originating in Perinatal Period ,Nutrition ,Reproductive health and childbirth ,Oral and gastrointestinal ,Zero Hunger ,Good Health and Well Being ,Female ,Humans ,Infant ,Newborn ,Dietary Supplements ,Food ,Formulated ,Gastrointestinal Microbiome ,Guinea-Bissau ,Infant Formula ,Infant Nutritional Physiological Phenomena ,Infant ,Low Birth Weight ,Intention to Treat Analysis ,Mothers ,Patient Safety ,Prospective Studies ,Thinness ,Treatment Outcome ,Uganda ,Malnutrition ,Randomized Controlled Trials as Topic ,General Science & Technology - Abstract
Childhood undernutrition is a major health burden worldwide that increases childhood morbidity and mortality and causes impairment in infant growth and developmental delays that can persist into adulthood. The first weeks and months after birth are critical to the establishment of healthy growth and development during childhood. The World Health Organization recommends immediate and exclusive breastfeeding (EBF). In infants for whom EBF may not meet nutritional and caloric demands, early, daily, small-volume formula supplementation along with breastfeeding may more effectively avoid underweight wasting and stunting in early infancy than breastfeeding alone. The primary objective of this randomized controlled trial is to evaluate the efficacy of formula for 30 days among low birth weight (LBW) infants
- Published
- 2022