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3. High CD90 (THY-1) expression positively correlates with cell transformation and worse prognosis in basal-like breast cancer tumors

Author

Lobba, Aline Ramos Maia, primary, Carreira, Ana Claudia Oliveira, additional, Cerqueira, Otto Luiz Dutra, additional, Fujita, André, additional, DeOcesano-Pereira, Carlos, additional, Osorio, Cynthia Aparecida Bueno, additional, Soares, Fernando Augusto, additional, Rameshwar, Pranela, additional, and Sogayar, Mari Cleide, additional

Published
2018
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4. Oral and Gastric Helicobacter Pylori: Effects and Associations

Author

Veiga, Nélio, primary, Pereira, Carlos, additional, Resende, Carlos, additional, Amaral, Odete, additional, Ferreira, Manuela, additional, Nelas, Paula, additional, Chaves, Claudia, additional, Duarte, João, additional, Cirnes, Luis, additional, Machado, José Carlos, additional, Ferreira, Paula, additional, and Correia, Ilídio J., additional

Published
2015
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6. COMT and MAO-A Polymorphisms and Obsessive-Compulsive Disorder: A Family-Based Association Study

Author

Sampaio, Aline Santos, primary, Hounie, Ana Gabriela, additional, Petribú, Kátia, additional, Cappi, Carolina, additional, Morais, Ivanil, additional, Vallada, Homero, additional, do Rosário, Maria Conceição, additional, Stewart, S. Evelyn, additional, Fargeness, Jesen, additional, Mathews, Carol, additional, Arnold, Paul, additional, Hanna, Gregory L., additional, Richter, Margaret, additional, Kennedy, James, additional, Fontenelle, Leonardo, additional, de Bragança Pereira, Carlos Alberto, additional, Pauls, David L., additional, and Miguel, Eurípedes Constantino, additional

Published
2015
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7. MicroRNAs Discriminate Familial from Sporadic Non-BRCA1/2 Breast Carcinoma Arising in Patients ≤35 Years

Author

Bastos, Elen Pereira, primary, Brentani, Helena, additional, Pasini, Fatima Solange, additional, Silva, Aderbal Ruy T., additional, Torres, Cesar Henrique, additional, Puga, Renato David, additional, Olivieri, Eloisa Helena Ribeiro, additional, Piovezani, Amanda Rusiska, additional, Pereira, Carlos Alberto de Bragança, additional, Machado-Lima, Ariane, additional, Carraro, Dirce Maria, additional, and Brentani, Maria Mitzi, additional

Published
2014
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8. Repair of Oxidative DNA Damage, Cell-Cycle Regulation and Neuronal Death May Influence the Clinical Manifestation of Alzheimer’s Disease

Author

Silva, Aderbal R. T., primary, Santos, Ana Cecília Feio, additional, Farfel, Jose M., additional, Grinberg, Lea T., additional, Ferretti, Renata E. L., additional, Campos, Antonio Hugo Jose Froes Marques, additional, Cunha, Isabela Werneck, additional, Begnami, Maria Dirlei, additional, Rocha, Rafael M., additional, Carraro, Dirce M., additional, de Bragança Pereira, Carlos Alberto, additional, Jacob-Filho, Wilson, additional, and Brentani, Helena, additional

Published
2014
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10. Nosocomial Bloodstream Infections in Brazilian Pediatric Patients: Microbiology, Epidemiology, and Clinical Features.

Author

Pereira, Carlos Alberto Pires, Marra, Alexandre R., Camargo, Luis Fernando Aranha, Pignatari, Antônio Carlos Campos, Sukiennik, Teresa, Behar, Paulo Renato Petersen, Medeiros, Eduardo Alexandrino Servolo, Ribeiro, Julival, Girão, Evelyne, Correa, Luci, Guerra, Carla, Carneiro, Irna, Brites, Carlos, Reis, Marise, de Souza, Marta Antunes, Tranchesi, Regina, Barata, Cristina U., and Edmond, Michael B.

Subjects
*NOSOCOMIAL infections, *BLOOD diseases, *MICROBIOLOGY, *EPIDEMIOLOGY, *JUVENILE diseases, *BRAZILIANS, *COAGULASE, *DISEASES
Abstract

Background: Nosocomial bloodstream infections (nBSIs) are an important cause of morbidity and mortality and are the most frequent type of nosocomial infection in pediatric patients. Methods: We identified the predominant pathogens and antimicrobial susceptibilities of nosocomial bloodstream isolates in pediatric patients (≤16 years of age) in the Brazilian Prospective Surveillance for nBSIs at 16 hospitals from 12 June 2007 to 31 March 2010 (Br SCOPE project). Results: In our study a total of 2,563 cases of nBSI were reported by hospitals participating in the Br SCOPE project. Among these, 342 clinically significant episodes of BSI were identified in pediatric patients (≤16 years of age). Ninety-six percent of BSIs were monomicrobial. Gram-negative organisms caused 49.0% of these BSIs, Gram-positive organisms caused 42.6%, and fungi caused 8.4%. The most common pathogens were Coagulase-negative staphylococci (CoNS) (21.3%), Klebsiella spp. (15.7%), Staphylococcus aureus (10.6%), and Acinetobacter spp. (9.2%). The crude mortality was 21.6% (74 of 342). Forty-five percent of nBSIs occurred in a pediatric or neonatal intensive-care unit (ICU). The most frequent underlying conditions were malignancy, in 95 patients (27.8%). Among the potential factors predisposing patients to BSI, central venous catheters were the most frequent (66.4%). Methicillin resistance was detected in 37 S. aureus isolates (27.1%). Of the Klebsiella spp. isolates, 43.2% were resistant to ceftriaxone. Of the Acinetobacter spp. and Pseudomonas aeruginosa isolates, 42.9% and 21.4%, respectively, were resistant to imipenem. Conclusions: In our multicenter study, we found a high mortality and a large proportion of gram-negative bacilli with elevated levels of resistance in pediatric patients. [ABSTRACT FROM AUTHOR]

Published
2013
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