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Your search keyword '"Stam, Cornelis J."' showing total 20 results
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20 results on '"Stam, Cornelis J."'

8. Single-Subject Grey Matter Graphs in Alzheimer's Disease

Author

Tijms, Betty M., primary, Möller, Christiane, additional, Vrenken, Hugo, additional, Wink, Alle Meije, additional, de Haan, Willem, additional, van der Flier, Wiesje M., additional, Stam, Cornelis J., additional, Scheltens, Philip, additional, and Barkhof, Frederik, additional

Published
2013
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9. MEG Network Differences between Low- and High-Grade Glioma Related to Epilepsy and Cognition

Author

van Dellen, Edwin, primary, Douw, Linda, additional, Hillebrand, Arjan, additional, Ris-Hilgersom, Irene H. M., additional, Schoonheim, Menno M., additional, Baayen, Johannes C., additional, De Witt Hamer, Philip C., additional, Velis, Demetrios N., additional, Klein, Martin, additional, Heimans, Jan J., additional, Stam, Cornelis J., additional, and Reijneveld, Jaap C., additional

Published
2012
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12. Characterization of Functional and Structural Integrity in Experimental Focal Epilepsy: Reduced Network Efficiency Coincides with White Matter Changes

Author

Otte, Willem M., primary, Dijkhuizen, Rick M., additional, van Meer, Maurits P. A., additional, van der Hel, Wilhelmina S., additional, Verlinde, Suzanne A. M. W., additional, van Nieuwenhuizen, Onno, additional, Viergever, Max A., additional, Stam, Cornelis J., additional, and Braun, Kees P.J., additional

Published
2012
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20. Increased Resting-State Functional Connectivity in Obese Adolescents; A Magnetoencephalographic Pilot Study.

Author

Dubbelink, Kim T. E. Olde, Felius, Abraham, Verbunt, Jeroen P. A., van Dijk, Bob W., Berendse, Henk W., Stam, Cornelis J., and Delemarre-van de Waal, Henriette A.

Subjects
OVERWEIGHT teenagers, MAGNETOENCEPHALOGRAPHY, OBESITY risk factors, TEENAGE girls, SYNCHRONIZATION, COGNITION disorders in adolescence, BRAIN function localization, METABOLIC syndrome, WEIGHT gain risk factors
Abstract

Background: Obesity is not only associated with metabolic abnormalities, but also with cognitive dysfunction and changes in the central nervous system. The present pilot study was carried out to investigate functional connectivity in obese and non-obese adolescents using magnetoencephalography (MEG). Methodology/Principal Findings: Magnetoencephalographic recordings were performed in 11 obese (mean BMI 38.8±4.6 kg/m2) and 8 lean (mean BMI 21.0±1.5 kg/m2) female adolescents (age 12-19 years) during an eyes-closed resting-state condition. From these recordings, the synchronization likelihood (SL), a common method that estimates both linear and non-linear interdependencies between MEG signals, was calculated within and between brain regions, and within standard frequency bands (delta, theta, alpha1, alpha2, beta and gamma). The obese adolescents had increased synchronization in delta (0.5-4 Hz) and beta (13-30 Hz) frequency bands compared to lean controls (Pdelta total = 0.001; Pbeta total = 0.002). Conclusions/Significance: This study identified increased resting-state functional connectivity in severe obese adolescents. Considering the importance of functional coupling between brain areas for cognitive functioning, the present findings strengthen the hypothesis that obesity may have a major impact on human brain function. The cause of the observed excessive synchronization is unknown, but might be related to disturbed motivational pathways, the recently demonstrated increase in white matter volume in obese subjects or altered metabolic processes like hyperinsulinemia. The question arises whether the changes in brain structure and communication are a dynamic process due to weight gain and whether these effects are reversible or not. [ABSTRACT FROM AUTHOR]

Published
2008
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