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2 results on '"Yongtai Gong"'

1. Plasma microRNAs as potential noninvasive biomarkers for in-stent restenosis.

Author

Meijiao He, Yongtai Gong, Jing Shi, Zhenwei Pan, Hui Zou, Danghui Sun, Xin Tu, Xiangyang Tan, Jianqiang Li, Weimin Li, Bin Liu, Jingyi Xue, Li Sheng, Chunhong Xiu, Ning Yang, Hongjie Xue, Xue Ding, Chengyuan Yu, and Yue Li

Subjects
Medicine, Science
Abstract

OBJECTIVE: To investigate whether microRNAs (miRs) can serve as novel biomarkers for in-stent restenosis (ISR). METHODS: This retrospective, observational single-centre study was conducted at the cardiovascular department of a tertiary hospital centre in the north of China. Follow-up coronary angiography at 6 to 12 months was performed in 181 consecutive patients implanted with drug-eluting stents. Fifty-two healthy volunteers served as the control group. The plasma miRs levels were analyzed by quantitative real-time PCR. Receiver-operating characteristic curve (ROC) analysis was performed to investigate the characters of these miRs as potential biomarkers of ISR. RESULTS: MiR-21 levels in ISR patients were significantly higher than those in non-ISR patients and healthy controls (P

Published
2014
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2. Plasma microRNAs as potential noninvasive biomarkers for in-stent restenosis

Author

Ning Yang, Zhenwei Pan, Bin Liu, Li Sheng, Yue Li, Hong-Jie Xue, Jing Shi, Meijiao He, Xin Tu, Wei-min Li, Yongtai Gong, Hui Zou, Xiang-Yang Tan, Chunhong Xiu, Jianqiang Li, Xue Ding, Danghui Sun, Chengyuan Yu, and Jingyi Xue

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Cardiology, lcsh:Medicine, Coronary Angiography, Gastroenterology, Coronary Restenosis, Restenosis, Angioplasty, Internal medicine, Blood plasma, Medicine and Health Sciences, Medicine, Humans, Angioplasty, Balloon, Coronary, lcsh:Science, Noninvasive biomarkers, Aged, Retrospective Studies, Multidisciplinary, medicine.diagnostic_test, business.industry, lcsh:R, Case-control study, Retrospective cohort study, Drug-Eluting Stents, Middle Aged, medicine.disease, Confidence interval, Interventional Cardiology, MicroRNAs, ROC Curve, Area Under Curve, Case-Control Studies, Angiography, Female, lcsh:Q, Radiology, business, Biomarkers, Research Article
Abstract

Objective To investigate whether microRNAs (miRs) can serve as novel biomarkers for in-stent restenosis (ISR). Methods This retrospective, observational single-centre study was conducted at the cardiovascular department of a tertiary hospital centre in the north of China. Follow-up coronary angiography at 6 to 12 months was performed in 181 consecutive patients implanted with drug-eluting stents. Fifty-two healthy volunteers served as the control group. The plasma miRs levels were analyzed by quantitative real-time PCR. Receiver-operating characteristic curve (ROC) analysis was performed to investigate the characters of these miRs as potential biomarkers of ISR. Results MiR-21 levels in ISR patients were significantly higher than those in non-ISR patients and healthy controls (P

Published
2014

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