1. Preparation and Properties of Poly(lactide-co-glycolide)/Bone Meals Composite Materials
- Author
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Zou Jian-peng, Zhou Zhong-cheng, Fan Xin, Ruan Jian-ming, and Chen Jian
- Subjects
Materials science ,Polymers and Plastics ,Biocompatibility ,General Chemical Engineering ,Materials Science (miscellaneous) ,digestive, oral, and skin physiology ,Composite number ,technology, industry, and agriculture ,Concentration effect ,Biomaterial ,macromolecular substances ,PLGA ,chemistry.chemical_compound ,Brittleness ,chemistry ,Flexural strength ,Materials Chemistry ,Composite material ,Fourier transform infrared spectroscopy - Abstract
Poly(lactide-co-glycolide)/bone meals composites using poly(lactide-co-glycolide) (PLGA) and bone meals (BM) as the starting materials were successfully prepared via solution dispersion method. Fourier Transform Infrared (FTIR) spectroscopy, X-ray diffraction and BET were used to characterize the resulting PLGA and bone meals. The mechanical properties of composites were carried out by the three-point-bending test, and the micrographs of cross-section of composites were observed using SEM. The results indicate that both the bending strength and modulus of PLGA/BM composites increased with bone meals increasing up to 10 wt%, then decreased with bone meals content, indicating that the fracture feature of PLGA/BM composites changed from typical brittle to ductile fracture when the bone meals content changed from 0 to 10 wt% and from ductile to brittle facture while bone meals content ranging from 10 to 20 wt%. It was further confirmed by SEM images of composites. The biocompatibility results show that result...
- Published
- 2010