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Castleman's disease was first reported by Castlemann et al. in 1954 as localized large benign hyperplastic mediastinal lymph nodes histologically characterized by hyperplasia of lymphoid follicles and capillary proliferation with endothelial hyperplasia. In 1972, Keller et al. subsequently divided Castleman's disease into two types according to the pathologic findings: the hyaline-vascular type and the plasma cell type. We report a case of hyaline-vascular type of Castleman's disease in a 29-year-old female.The patient presented with 11 years history of a large tumor on the right side of her neck. The tumor size had not increasad for 11 years and she had no symptoms except for neck swelling. CT and MRI showed a single mass (60×50×30mm), and laboratory data were within normal ranges. The tumor was surgically resected and histologically identified as a hyaline-vascular type of Castleman's disease. Postoperatively the patient is well with no recurrence for one year.

Although most tumors in the parapharyngeal space are benign, a few malignant tumors have been reported. Malignant lymphomas are very rare, and Burkitt's lymphoma in the parapharyngeal space has been reported only once in the world literature. Here we describe a patient with Burkitt's lymphoma of the parapharyngeal space.A 63-year-old male visited us because of a rapidly increasing mass at the angle of his mandible. MRI showed a large tumor occupying the parapharyngeal space. The FNA report was probable malignant tumor but perhaps not malignant lymphoma. We suspected carcinoma of the parapharyngeal space and resected it through a neck incision. Histological examination showed Burkitt's lymphoma, and the patient was referred to the department of hematology in our hospital.

It is known that ear piercing can cause various complications such as infection, allergic contact dermatitis, granulation, dermoid cyst formation buried earring and so on. We describe a case of earlobe keloid caused by ear piercing. The patient, an 18-year-old female, visited our hospital complaining of a large tumor hanging from the left earlobe. The tumor was excised and a histological examination revealed keloid tissue with subcutaneous clusters of lymphocytes.An immunohistochemical study of the keloid tissue was performed using a polyclonal antibody against human IgG and IgE. Numerous IgE positive cells, presumably mast cells, were found below the epidermis, suggesting that the keloid was still active and still sensitized by some stimulation. The inflammatory response seemed to have contributed to formation of the large keloid.

A 28-year-old male in good general health complained of nasal bleeding. Rhinoscopy revealed a dark red colored tumor with irregular surface in the left nasal cavity. The large tumor of 4×3×3cm in size and 15 grams in weight was surgically removed under general anesthesia. It was confirmed that the tumor originated from the upper part of the nasal septum. The histological diagnosis was a mixed tumor composed of myoepithelial cells with glandular elements. After removal of the tumor, no recurrence has been observed.

A Japanese male aged 57, complaining of sudden facial palsy on the right side, was diagnosed preoperatively as “cholesteatoma”. During exploratory tympanotomy a large tumor was found along the Fallopian canal. The histological examination of the tumor revealed facial neurinoma. Difficulty in diagnosis of facial neurinoma was discussed from the viewpoint of the coexistance of cholesteatoma. A search of the literature failed to reveal a report of a similar case.