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A 67-year-old Brazilian man of African ancestry and his 60-year-old sister both presented with choreiform movements, although in the man these were significantly overshadowed by additional parkinsonism. The man also had a history of four epileptic seizures. Neurological examination in each also found slow saccades and a dysexecutive syndrome. Genetic tests for Huntington’s disease were negative but were positive for Huntington’s disease-like 2. There are various genetic causes of chorea diseases, and their correct identification is important for appropriate clinical management and genetic counselling.

A 69-year-old man presented with a reduced level of consciousness and left hemiparesis immediately after a percutaneous CT-guided transthoracic needle lung biopsy, performed to investigate an interstitial pulmonary disease. CT scan of the head (figure 1A, B) showed small, 1–2 mm sparse and linearly arranged hypodensities, suggesting air emboli in the anterior and posterior territories of the right cerebral hemisphere circulation, without ischaemic lesions. However, MR brain imaging (figure 1C, D) ultimately confirmed stroke secondary to gas embolisation in the same territory. Echocardiography, carotid and vertebral arterial duplex scans, and routine laboratory tests were normal. We gave him aspirin, but his left leg weakness persisted. He died 1 year later from pulmonary complications of the primary …