1. Impact of an enhanced recovery after surgery program with a multimodal analgesia care pathway on opioid prescribing and clinical outcomes for patients undergoing colorectal surgery.
- Author
-
Collinsworth AW, Kouznetsova M, Hall L, Robinson C, Ogola GO, Turner A, Priest EL, Hart C, Böing EA, Wan GJ, Peters WR, and Masica AL
- Abstract
Background: Opioids are a mainstay for acute pain management, but their side effects can adversely impact patient recovery. Multimodal analgesia (MMA) is recommended for treatment of postoperative pain and has been incorporated in enhanced recovery after surgery (ERAS) protocols. The objective of this quality improvement study was to implement an MMA care pathway as part of an ERAS program for colorectal surgery and to measure the effect of this intervention on patient outcomes and costs., Methods: This pre-post study included 856 adult inpatients who underwent an elective colorectal surgery at three hospitals within an integrated healthcare system. The impact of ERAS program implementation on opioid prescribing practices, outcomes, and costs was examined after adjusting for clinical and demographic confounders., Results: Improvements were seen in MMA compliance (34.0% vs 65.5%, P < 0.0001) and ERAS compliance (50.4% vs 57.6%, P < 0.0001). Reductions in mean days on opioids (4.2 vs 3.2), daily (51.6 vs 33.4 mg) and total (228.8 vs 112.7 mg) morphine milligram equivalents given during hospitalization, and risk-adjusted length of stay (4.3 vs 3.6 days, P < 0.05) were also observed., Conclusions: Implementing ERAS programs that include MMA care pathways as standard of care may result in more judicious use of opioids and reduce patient recovery time., Competing Interests: Dr. Wan is the Global Head of Evidence Generation and Data Sciences at Mallinckrodt Pharmaceuticals. Ms. Böing previously served as the Senior Manager for Health Economics and Outcomes Research (HEOR) and Real-World Evidence at Mallinckrodt Pharmaceuticals and is currently the Director of Global HEOR for Rare Disease at Ipsen. Dr. Collinsworth is currently a Senior Research Scientist at 3M. The other authors declare no potential conflicts of interest., (Copyright © 2023 Baylor University Medical Center.)
- Published
- 2023
- Full Text
- View/download PDF