48 results on '"Welsh, Michael J."'
Search Results
2. A model for stimulation of enzyme activity by a competitive inhibitor based on the interaction of terazosin and phosphoglycerate kinase 1
3. Elastic mucus strands impair mucociliary clearance in cystic fibrosis pigs
4. Cellular and molecular architecture of submucosal glands in wild-type and cystic fibrosis pigs
5. Cystic fibrosis carriers are at increased risk for a wide range of cystic fibrosis-related conditions
6. Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling
7. Gel-forming mucins form distinct morphologic structures in airways
8. Relationships among CFTR expression, HCO 3 − secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies
9. pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37
10. Neuronal necrosis is regulated by a conserved chromatin-modifying cascade
11. Protons are a neurotransmitter that regulates synaptic plasticity in the lateral amygdala
12. Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs
13. CFTR-deficient pigs display peripheral nervous system defects at birth
14. A microRNA network regulates expression and biosynthesis of wild-type and ΔF508 mutant cystic fibrosis transmembrane conductance regulator
15. Detecting activity-evoked pH changes in human brain
16. Human–mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR-ΔF508 processing and alter its gating defect
17. Human cystic fibrosis airway epithelia have reduced Cl − conductance but not increased Na + conductance
18. Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth
19. TRPA channels distinguish gravity sensing from hearing in Johnston's organ
20. Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits
21. Acute regulation of tight junction ion selectivity in human airway epithelia
22. Loss of Bardet–Biedl syndrome proteins alters the morphology and function of motile cilia in airway epithelia
23. Acid-sensing ion channels interact with and inhibit BK K + channels
24. Processing and function of CFTR-ΔF508 are species-dependent
25. Eukaryotic operon-like transcription of functionally related genes in Drosophila
26. Acid-sensing ion channel 1a is a postsynaptic proton receptor that affects the density of dendritic spines
27. A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia
28. ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity
29. Normal gating of CFTR requires ATP binding to both nucleotide-binding domains and hydrolysis at the second nucleotide-binding domain
30. Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a
31. Overexpression of acid-sensing ion channel 1a in transgenic mice increases acquired fear-related behavior
32. Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia
33. Propagation of infectious human papillomavirus type 16 by using an adenovirus and Cre/LoxP mechanism
34. Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia
35. cAMP-dependent protein kinase phosphorylation of the acid-sensing ion channel-1 regulates its binding to the protein interacting with C-kinase-1
36. Drosophila DEG/ENaC pickpocket genes are expressed in the tracheal system, where they may be involved in liquid clearance
37. CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo
38. Discovery of five conserved β-defensin gene clusters using a computational search strategy
39. Heteromultimers of DEG/ENaC subunits form H + -gated channels in mouse sensory neurons
40. DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature
41. The osmolyte xylitol reduces the salt concentration of airway surface liquid and may enhance bacterial killing
42. Regulation of CFTR Cl − channel gating by ATP binding and hydrolysis
43. A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution
44. Disruption of the β subunit of the epithelial Na + channel in mice: Hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype
45. Production of β-defensins by human airway epithelia
46. A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
47. Protein phosphatase 2C dephosphorylates and inactivates cystic fibrosis transmembrane conductance regulator
48. Calcium-dependent regulator protein: Localization in mitotic apparatus of eukaryotic cells
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