Search

To study effect of symbicort turbuhaler (ST) combined with montelukast on pulmonary function and serum cytokine levels in patients with acute stage of bronchial asthma(ASBA). 86 patients with ASBA who were treated in our hospital from February 2015 to August 2017 were selected as research subjects. The patients were divided into the observation group (n=43) and the control group (n=43) according to the random number table method. The control group was treated with ST, and the observation group was treated with montelukast on the basis of the control group, two groups were treated for 3 months. The lung function, cytokine levels, cough score, St. George's respiratory disease questionnaire (SGRQ) before treatment and 3 months after treatment and drug safety were compared between the two groups. After treatment, the levels of forced expiratory volume (FEV1), forced vital capacity (FVC) and FEV1/FVC in the two groups were increased significantly compared with those before treatment, and the observation group was higher than that of the control group (P<0.05). After treatment, the levels of interleukin-4 (IL-4), interleukin-5 (IL-5), interferon-酌 (INF-酌) and tumor necrosis factor-琢 (TNF-琢) in the two groups were all lower than those before treatment, and the observation group was lower than that in the control group (P<0.05). After treatment, the scores of cough in two groups were significantly higher than before treatment, and the observation group was significantly higher than the control group(P<0.05). After treatment, the scores of SGRQ in two groups were significantly lower than before treatment, and the observation group was significantly lower than the control group(P<0.05). The total incidence of adverse reactions in the observation group was 20.93%, and there was no statistical difference compared with 16.28% of the control group (P>0.05). ST combined with montelukast can effectively improve the symptoms of the ASBA patients, alleviate the inflammatory reaction of the body and improve the pulmonary function and quality of life of the patients at the same time. [ABSTRACT FROM AUTHOR]

To understand the etiological detection and epidemiological regularity of respiratory viruses in children with respiratory tract infections, so as to provide etiological basis for the prevention, diagnosis and treatment of respiratory tract infections in children. 280 children with respiratory tract infections who were admitted to General Hospital of Central Theater Command of PLA from January 2016 to December 2017 were selected as the study subjects. The detection of respiratory viruses in children with respiratory tract secretions were analyzed, and the relationship between respiratory viral infection and age, season and disease type in children with respiratory tract infection were analyzed. 98 positive specimens were detected in 280 children with respiratory tract infection, the positive rate was 35.00%. 2 viruses were detected in 2 samples, and the positive rate of mixed infection was 0.71%. Among all virus types, the respiratory syncytial virus (RSV) had the highest positive rate. The highest positive rate of viral infection was found in children younger than 1 year old, which was significantly different from that in other age groups (P<0.05). The positive rate of respiratory tract infection in spring and winter was significantly higher than that in summer and autumn (P<0.05). The positive rates of viral infection in children with different respiratory tract infections were significantly different (P<0.05). The positive rate of virus infection in children with asthmatic pneumonia, bronchiolitis and pneumonia was higher. RSV is the main pathogen of respiratory viral infection in children with respiratory tract infection. Infants younger than 1 year old are more susceptible to infection. Spring and winter are the high incidence seasons. The positive rates of virus infection in children with pneumonia, bronchiolitis and asthmatic pneumonia are higher. [ABSTRACT FROM AUTHOR]

Objective: To analyze the composition and trend of disease death among residents in the Heilongjiang Province from 2013 to 2017, and therefore provide reference data to improve the awareness of disease prevention and treatment and strengthen the healthy living concept of residents in the Heilongjiang Province. Methods: The statistical methods were used to analyze the changes the composition and trend of disease death among residents elicited from the National Health Statistics Network Direct Reporting System. Results: The sex ratio of death in the whole province is higher than that in females. The death rate of residents in the province is above 70 years old. The top three causes of death in the province were: circulatory diseases, tumors, and respiratory diseases. Furthermore, cardiovascular disease, acute myocardial infarction, and coronary heart disease have higher mortality in circulatory diseases. Conclusions: Strengthening the prevention and treatment of circulatory diseases, malignant tumors and respiratory diseases may be helpful to reduce the incidence and death of diseases. [ABSTRACT FROM AUTHOR]

Bronchial asthma is a worldwide chronic airway inflammatory respiratory disease, in recent years, with the increase of air pollution and the increasing number of smokers, the incidence of the disease has increased year by year, which has attracted more and more people’s attention. Bronchial asthma is caused by a variety of factors such as genetic factors, biological factors, psychological factors and other factors, with the deepening of research, great progress has been made in the study of the effect of psychological factors on bronchial asthma, there are obvious personality characteristics and emotional disorders in the patients with bronchial asthma, and the patient’s personality characteristics and emotional disorders will have a certain impact on the patient’s condition and quality of life. In view of this, this article gives a brief account of the personality characteristics, emotional characteristics and its influence on the disease for the clinical reference. [ABSTRACT FROM AUTHOR]

Objective: To explore the effect of particles matters in the ambient air pollution on the hospital emergency treatment for respiratory diseases in Beijing. Methods: The data of the daily hospital emergency treatment for respiratory diseases fromthe PLA 305 Hospital and the clinic of eighth military cadres department of the West Third Ring general staff department, and the data of air and meteorological conditions from Beijing Municipal Environmental Monitoring Center were collected. The case-crossover design was used to analyse the data. Results: In the control of temperature and relative humidity, the results from unidirectional retrospective 1:1 matched case-crossover analysis showed that the fine particulates pollution of lag 0 days affected chronic bronchitis, asthma, chronic obstructive pulmonary disease, the OR values of the hospital emergency room visits for those diseases were 1.032, 1.033,1.035 with each increased 10 ug/m3 increment of particulate matters respectively. Conclusion: The elevated level of fine particulates pollution in atmospheric concentration can increase the hospital emergency treatment for the respiratory disease associated with chronic bronchitis, asthma, and chronic obstructive pulmonary disease in Beijing. [ABSTRACT FROM AUTHOR]