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During examinations of 479 patients referred for atopic dermatitis and 520 with urticaria it was found that in the first group coexistence of these diseases was frequently occurring, and in the second group it was rare. Food allergens caused slightly more frequently episodes of urticaria than exacerbations of atopic dermatitis. Coexistence of urticaria with atopic dermatitis was particularly frequent in patients: a) with a high IgE titre, b) with a history of allergy in the families of both parents, c) in patients with respiratory allergy associated with skin lesions.

An additional set for testing of patients with eczema was prepared. This set comprised 38 compounds, including 12 components of perfumes and food flavours, 12 components of rubber or plastic materials, 9 drugs for external use and 5 other agents. The set was used for testing of 306 patients and in nearly a half of the cases positive results were obtained.

In a group of 535 children and 103 adult patients with atopic dermatitis no differences were observed between persons with normal and raised IgE level with respect to incidence of lesions in the first or the first three months of life, the total number of the positive RAST results and the most intense reactions, that is 4 degrees, the percent of helper and suppressor T-cells, duration of remission, darkening of lower eyelids, cheilitis, involvement of the hands, the feet, the elbow flexures or knee flexures. On the other hand, in individuals with raised IgE level, especially in patients with IgE level tenfold higher or more than normal, the co-existence of alergic diseases of the respiratory system, the appearance of itching after sweating, itching after emotion, pityriasis alba, and eczema of breasts were