1. Facial emotion perception in individuals with clinical high risk for psychosis compared with healthy controls, first-episode psychosis, and in predicting psychosis transition: A systematic review and meta-analysis.
- Author
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Tsui, Harry Kam Hung, Luk, Siu Lee, Hsiao, Janet, and Chan, Sherry Kit Wa
- Subjects
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EMOTION recognition , *PSYCHOSES , *EMOTIONS , *SOCIAL perception , *AVERSION , *FACIAL expression & emotions (Psychology) - Abstract
• CHR had overall facial emotion perception impairments compared to HC, but less severe than FEP. • CHR who transitioned performed significantly poorer in baseline performance than those did not. • CHR showed specific deficit in perceiving all emotions except surprise compared to HC. • FER significantly performed poorer in perceiving fear expression compared to CHR. • Some misattribution rates could predict transition risk and warranted further study. Facial emotion perception deficits, a possible indicator of illness progression and transdiagnostic phenotype, were examined in high-risk psychosis (CHR) patients through a systematic review and meta-analysis of 35 studies (2567 CHR individuals, 1103 non-transitioned [CHR-NT], 212 transitioned [CHR-T], 512 first-episode psychosis [FEP], and 1936 healthy controls [HC]). CHR showed overall (g = -0.369 [95 % CI, -0.485 to -0.253]) and specific impairments in detecting anger, disgust, fear, happiness, neutrality, and sadness compared to HC, except for surprise. FEP revealed a general deficit than CHR (g = -0.378 [95 % CI, -0.509 to -0.247]), and CHR-T displayed more pronounced baseline impairments than CHR-NT (g = -0.217 [95 % CI, -0.365 to -0.068]). FEP only exhibited a poorer ability to perceive fear, but not other individual emotions, compared to CHR. Similar performances in perceiving individual emotions were observed regardless of transition status (CHR-NT and CHR-T). However, literature comparing the perception of individual emotions among FEP, CHR-T, and CHR is limited. This study primarily characterized the general and overall impairments of facial emotion perception in CHR which could predict transition risk, emphasizing the need for future research on multimodal parameters of emotion perception and associations with other psychiatric outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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