1. Trajectories of quality of life, life satisfaction, and psychological adjustment after prostate cancer
- Author
-
Suzanne K. Chambers, Jeff Dunn, Peter D. Baade, Gary A. Wittert, Melissa K. Hyde, Joanne F. Aitken, Shu-Kay Ng, and Mark Frydenberg
- Subjects
Gerontology ,Oncology ,Paper ,Male ,medicine.medical_specialty ,longitudinal ,medicine.medical_treatment ,Experimental and Cognitive Psychology ,Personal Satisfaction ,Emotional Adjustment ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Quality of life ,psychological distress ,Survivorship curve ,Internal medicine ,Surveys and Questionnaires ,Adaptation, Psychological ,medicine ,cancer ,Humans ,Oncology & Carcinogenesis ,030212 general & internal medicine ,Aged ,prostate ,Prostatectomy ,business.industry ,Life satisfaction ,Prostatic Neoplasms ,Middle Aged ,medicine.disease ,3. Good health ,Psychiatry and Mental health ,quality of life ,030220 oncology & carcinogenesis ,Papers ,oncology ,Quality of Life ,Anxiety ,Life course approach ,medicine.symptom ,1103 Clinical Sciences, 1112 Oncology and Carcinogenesis, 1701 Psychology ,business ,Sexual function - Abstract
Background To describe trajectories of health-related quality of life (QoL), life satisfaction, and psychological adjustment for men with prostate cancer over the medium to long term and identify predictors of poorer outcomes using growth mixture models. Methods One-thousand sixty-four (82.4% response) men diagnosed with prostate cancer were recruited close to diagnosis and assessed over a 72-month (6-year) period with self-report assessment of health-related QoL, life satisfaction, cancer-related distress, and prostate specific antigen anxiety. Urinary, bowel, and sexual function were also assessed using validated questionnaires. Results Poorer physical QOL was predicted by older age, lower education, lower income, comorbidities, and receiving hormone therapy. Lower life satisfaction was related to younger age, lower income, not being partnered, and comorbidities. Poorer psychological trajectories were predicted by younger age, lower income, comorbidities, and receiving radical prostatectomy or brachytherapy. Better urinary, bowel, and sexual function were related to better global outcomes over time. Anxiety about prostate specific antigen testing was rare. Conclusions Distinct trajectories exist for medium- to long-term QoL, life satisfaction, and psychological adjustment after prostate cancer; with age and socioeconomic deprivation playing a differential role in men's survivorship profile and the impact of functional status on outcomes increasing over time. These results reinforce the need for an appraisal of men's life course in addition to treatment side effects when planning survivorship care after cancer.
- Published
- 2017