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Start Over Author "Bueno, O." Journal psychopharmacology
6 results on '"Bueno, O."'

5. δ-Tetrahydrocannabinol, ethanol, and amphetamine as discriminative stimuli-generalization tests with other drugs.

Author

Bueno, O., Carlini, E., Finkelfarb, Estera, and Suzuki, Jacira

Abstract

Three groups of rats (A, B, C) were trained in a T-maze to discriminate between drug- and control solution-induced internal discriminative stimuli. The drugs used to induce discriminative stimuli were: δ-THC, 5.0 mg/kg (Group A); ethanol, 1.2 g/kg (Group B), and amphetamine, 1.0 mg/kg (Group C). After discrimination acquisition several drugs were tested for generalization in each group. Group A was tested with δ-THC, CBD, CBN, ethanol, pentobarbital, chlorpromazine, amphetamine, and apomorphine; only δ-THC and CBN induced δ-THC-like responses. Group B was tested with δ-THC, δ-THC, CBD, CBN, pentobarbital, and amphetamine; pentobarbital induced ethanol-like response. Group C was tested with δ-THC, apomorphine, and ethanol; δ-THC and apomorphine elicited amphetamine-like responses. [ABSTRACT FROM AUTHOR]

Published
1976
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6. δ9-Tetrahydrocannabinol, ethanol, and amphetamine as discriminative stimuli-generalization tests with other drugs

Author

Bueno, O. F. A., Carlini, E. A., Finkelfarb, Estera, and Suzuki, Jacira S.

Abstract

Three groups of rats (A, B, C) were trained in a T-maze to discriminate between drug- and control solution-induced internal discriminative stimuli. The drugs used to induce discriminative stimuli were: d9-THC, 5.0 mg/kg (Group A); ethanol, 1.2 g/kg (Group B), and amphetamine, 1.0 mg/kg (Group C). After discrimination acquisition several drugs were tested for generalization in each group. Group A was tested with d8-THC, CBD, CBN, ethanol, pentobarbital, chlorpromazine, amphetamine, and apomorphine; only d8-THC and CBN induced d9-THC-like responses. Group B was tested with d9-THC, d8-THC, CBD, CBN, pentobarbital, and amphetamine; pentobarbital induced ethanol-like response. Group C was tested with d9-THC, apomorphine, and ethanol; d9-THC and apomorphine elicited amphetamine-like responses.

Published
1976
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