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The paper presents a new high-resolution (up to decadal) palaeoecological evidence based on detailed AMS radiocarbon dating, plant macrofossils, testate amoebae, loss on ignition, peat humification, elemental and stable isotopic records, obtained from a palsa peatland located in vicinities of Igarka town. This gave us a unique possibility to examine the mid-to late Holocene environmental changes in a poorly investigated area in Yenisei Siberia. The obtained data show that the peatland initiation occurred at about 6350 cal yr BP by paludification of a larch forest in the conditions of climate warming and high surface wetness, possibly, due to permafrost thaw. The first sign of palsa formation occurred about 5360 cal yr BP and coincided with the temperature decrease, wetter and anoxic conditions in peatland. After several phases of uplifts (and relatively dryer conditions) and partial thawing and subsidence of its surface (wetter conditions) between 5360 and 2250 cal yr BP, the continuous rise of the perennial frost mound (up to the height of 5 m) accomplished by drying its surface and colonization by drought-resistant plant species, evidently, encouraged by the climate cooling and permafrost aggradation during the last two millennia. The high-resolution analyses of elemental (C and N) and stable isotope content (δ13C and δ15N) of the peat sequence revealed the strong linkages between the plant composition and mineralization/humification processes. Our multi-proxy study revealed detailed features of peat accumulation patterns driven by multiple interrelated allogenic and autogenic forcings, influencing changes in peat macroelement content and stable isotope composition. [ABSTRACT FROM AUTHOR]