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Abstract: The pattern of Holocene environmental changes in the Asian monsoon margin on a millennial timescale remains controversial. Based on lithological characteristics and sedimentological proxies, we reconstructed Holocene-effective humidity changes and the lake evolution of Huahai Lake in the marginal area of the Asian monsoon in the Hexi Corridor of NW China. Our results show that alluvial and aeolian deposition before 10.4 cal ka BP indicate an arid environment, that lacustrine deposition from 10.4 to 8.8 cal ka BP indicates a transition from an arid to a humid environment, and that lacustrine deposition from 8.8 to 5.5 cal ka BP occurred during the most humid conditions, indicated by proxy records (grain size, carbonate, TOC, and C/N). After 5.5 cal ka BP, a depositional hiatus implicates an arid environment in the late Holocene. Holocene environmental changes on millennial timescales in Huahai Lake imply that climate was arid to humid in the early Holocene, most humid in the mid-Holocene and arid in the late Holocene. These moisture changes were influenced by the Asian monsoon, particularly the transportation of water vapor by the Indian monsoon. In addition, these moisture changes could have been affected by westerly winds that could have contributed to the water vapor supply to this region during the mid-Holocene. The most humid conditions that occurred in the study area during the mid-Holocene may have been caused by strong westerlies and low levels of evaporation. [Copyright &y& Elsevier]