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The chemical investigation of the MeOH extract from the bryozoan B. dentata MeOH yielded tambjamines A (1), C (3), D (4), K (6), aldehyde 8 and the new tambjamine J1(9), while the extract of its predator, the nudibranch Tambja stegosauriformis, yielded tambjamines C and K, along with aldehyde 8. Furodisinin lactone (11) was isolated from the nudibranch Hypselodoris lajensis, a compound previously isolated from Dysidea sponges. The alkaloid 2,5,6-tribromo-N-methylgramine (12) was isolated from the nudibranch Okenia zoobotryon and from its prey, the bryozoan Zoobotryon verticillatum, the only source of 12 previously known.

The application of one-dimensional proton high-resolution magic angle spinning (1H HR-MAS) NMR combined with a typical advantages of solid and liquid-state NMR techniques was used as input variables for the multivariate statistical analysis. In this paper, different cultivars of beans (Phaseolus vulgaris) developed and in development by Embrapa - Arroz e Feijao were analyzed by 1H HR-MAS, which have been demonstrated to be a valuable tool in its differentiation according chemical composition and avoid the manipulation of the samples as used in other techniques.

Experimental procedures based on factorial design and surface response methodology were applied to establishe experimental conditions for the decomposition of a 1:400 (v/v) Supocade® (chlorfenvinphos 13.8% and cypermethrin 2.6%) solution, used to control cattle ticks. Experiments exploring photo-oxidative reactions were performed with and without UV radiation, fixing exposition time and pesticide volume, and varying the oxidant mixture. The use of 3.6 mmol L-1 Fe2+ plus 1.9 mol L-1 H2O2 plus UV radiation provided destruction of 94% of the original carbon content and reduction of aromatic, aliphatic and carbinolic compounds, evaluated by determination of residual carbon content by ICP OES and NMR analysis.

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:48:33Z No. of bitstreams: 1 S0100-40422004000300016.pdf: 381839 bytes, checksum: c2621b29331946b6c28b12fb50ab7b00 (MD5) Made available in DSpace on 2013-08-22T18:48:33Z (GMT). No. of bitstreams: 1 S0100-40422004000300016.pdf: 381839 bytes, checksum: c2621b29331946b6c28b12fb50ab7b00 (MD5) Previous issue date: 2004-06-01 Made available in DSpace on 2013-09-30T19:38:29Z (GMT). No. of bitstreams: 2 S0100-40422004000300016.pdf: 381839 bytes, checksum: c2621b29331946b6c28b12fb50ab7b00 (MD5) S0100-40422004000300016.pdf.txt: 23095 bytes, checksum: 294c30efdd227218ece28d420c1a8725 (MD5) Previous issue date: 2004-06-01 Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T15:10:19Z No. of bitstreams: 2 S0100-40422004000300016.pdf: 381839 bytes, checksum: c2621b29331946b6c28b12fb50ab7b00 (MD5) S0100-40422004000300016.pdf.txt: 23095 bytes, checksum: 294c30efdd227218ece28d420c1a8725 (MD5) Made available in DSpace on 2014-05-20T15:10:19Z (GMT). No. of bitstreams: 2 S0100-40422004000300016.pdf: 381839 bytes, checksum: c2621b29331946b6c28b12fb50ab7b00 (MD5) S0100-40422004000300016.pdf.txt: 23095 bytes, checksum: 294c30efdd227218ece28d420c1a8725 (MD5) Previous issue date: 2004-06-01 Drug therapy involving bone tissue diseases is difficult, calling for the design of specific drugs. The present paper is a brief review of a new site-directed system termed ODDS (osteotropic drug delivery system), based on a latenciation process, using bisphosphonates as bone carriers. This is an important tool for the rational prodrug design for obtaining selective drugs. Universidade Estadual Paulista Júlio de Mesquita Filho Faculdadade de Ciências Farmacêuticas Departamento de Fármacos e Medicamentos Universidade Federal de São Carlos (UFSCar) Instituto de Química Departamento de Química Universidade de São Paulo Faculdade de Ciências Farmacêuticas Departamento de Farmácia Universidade Estadual Paulista Júlio de Mesquita Filho Faculdadade de Ciências Farmacêuticas Departamento de Fármacos e Medicamentos

Methanol extract obtained from Kielmeyera variabilis stems showed significant molluscicidal activity against Biomphalaria glabrata. The phytochemical studies of the plants stem to the isolation of three xanthones (assiguxanthone-B, kielcorin and 1,3,5,6-tetrahtydroxy-2-prenylxanthone) and a organic acid (2,5-dihydroxy benzoic acid). The structures of these compounds were identified by IR, MS, ¹H and 13C NMR spectral analysis and comparison with literature data.

Nickel nanoparticles supported on amorphous silica ceramic matrix were synthesized by the polymeric precursor method. The nanostructure was characterized by NMR, BET, XRD, SEM, TEM, and flame atomic absorption spectrometry techniques. It was observed a dependence of the crystallite size on the thermal annealing, under a N2 atmosphere. The materials presented a high catalytic activity and selectivity upon the beta-pinene hydrogenation reaction. The magnetic hystereses were also correlated with the morphology of the processed material.

The main purpose of this work is to describe the use of the technique Site-Specific Natural Isotopic Fractionation of hydrogen (SNIF-NMR), using ²H and ¹H NMR spectroscopy, to investigate the biosynthetic origin of acetic acid in commercial samples of Brazilian vinegar. This method is based on the deuterium to hydrogen ratio at a specific position (methyl group) of acetic acid obtained by fermentation, through different biosynthetic mechanisms, which result in different isotopic ratios. We measured the isotopic ratio of vinegars obtained through C3, C4, and CAM biosynthetic mechanisms, blends of C3 and C4 (agrins) and synthetic acetic acid.

Herein we describe the isolation of homarine and piridiniumbetaine B from the sponge Aaptos sp. Although homarine has a common occurrence among animals, piridiniumbetaine B was only recently isolated from the marine sponge Agelas dispar. The isolation of piridiniumbetaine B from two taxonomically distant marine sponges corroborate previous assumptions that such betaines should be regarded rather as primary metabolites. We have also isolated (9-[5'-(methylthio)-beta-D-xylofuranosyl]adenine (xylosyl-MTA) from the mantle of a nudibranch identified as Doris aff. verrucosa. The occurrence of xylosyl-MTA in the mantle of this animal strongly suggests that it is the same nudibranch species described for the Mediterranean sea. We have been unable to detect any other compound in the mantle extract of D. aff. verrucosa other than xylosil-MTA and sterols. GC-MS analysis of the sterol fraction from the nudibranch and its prey, the sponge Hymeniacidon aff. heliophila, revealed the occurrence of the ubiquitous sterols, cholesterol, brassicasterol, cholestanol, 24-methylcholesterol and 24-ethylcholesterol, as the only common metabolites, therefore precluding any assumption concerning the sequestration of secondary metabolites by the nudibranch from H. aff. heliophila.