1. X-ray phototherapy for canine brain masses
- Author
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A, Norman, M, Ingram, R G, Skillen, D B, Freshwater, K S, Iwamoto, and T, Solberg
- Subjects
Brain Neoplasms ,Biopsy ,Organ Size ,Astrocytoma ,X-Ray Therapy ,Radiation Dosage ,Survival Rate ,Random Allocation ,Dogs ,Meningeal Neoplasms ,Animals ,Dog Diseases ,Meningioma ,Tomography, X-Ray Computed - Abstract
Brain masses diagnosed in 47 pet dogs as tumors by CT scans, and confirmed in 12 dogs by necropsies, were injected with iodinated contrast media and treated by a modified CT scanner, the CTRx. Twenty-six dogs that received six or more weekly treatments of about 5.6 Gy per fraction, of which about 25% was contributed by radiation from the iodine, for a median total dose of 39 Gy, had a median survival of 230 days. This compares well with the 150 days reported for 25 dogs given 46-48 Gy of cobalt-60 radiation to the whole brain, and is significantly greater than the 6 to 13 days in untreated historic controls.
- Published
- 1997