1. Regional metastasis in head and neck squamous cell carcinoma: revised value of US with US-guided FNAB.
- Author
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Takes RP, Knegt P, Manni JJ, Meeuwis CA, Marres HA, Spoelstra HA, de Boer MF, Bruaset I, van Oostayen JA, Laméris JS, Kruyt RH, Joosten FB, van Krieken JH, Bosman FT, Henzen-Logmans SC, Wiersma-van Tilburg JM, Hermans J, and Baatenburg de Jong RJ
- Subjects
- Adult, Aged, Aged, 80 and over, Carcinoma, Squamous Cell diagnosis, Female, Humans, Lymphatic Metastasis diagnosis, Lymphatic Metastasis diagnostic imaging, Male, Middle Aged, Neck, Observer Variation, Palpation, Prospective Studies, Sensitivity and Specificity, Ultrasonography, Biopsy, Needle, Carcinoma, Squamous Cell diagnostic imaging, Carcinoma, Squamous Cell secondary, Head and Neck Neoplasms pathology
- Abstract
Purpose: To verify the acclaimed accuracy of ultrasound (US) combined with US-guided fine-needle aspiration biopsy (FNAB) in the detection of lymph node metastasis in the neck and to evaluate the interobserver variability., Materials and Methods: In a prospective, multicenter study of 185 patients with head and neck squamous cell carcinoma, US (n=238 neck sides) with US-guided FNAB (n=178 neck sides) was used for evaluation of the lymph node status of the neck. Findings were correlated with those of histopathologic examination in 238 neck sides., Results: US with US-guided FNAB had a sensitivity of 77% and a specificity of 100%. Nineteen of 178 aspirations were nondiagnostic. There were no significant differences between the four participating hospitals or the individual sonologists (P>.05)., Conclusion: Sensitivity of US with US-guided FNAB was slightly lower compared with previous reports. Specificity was similar to previous reports. Interobserver variability appeared to be low. The validity of US with US-guided FNAB is high and warrants widespread use of the procedure for evaluation of the neck.
- Published
- 1996
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