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41 results on '"M.C. Leonardi"'

1. PO-1091 Positive axillary non-sentinel nodes predictors in breast cancer patients after neoadjuvant therapy

Author

Damaris Patricia Rojas, Sara Gandini, C. Arrobbio, Viviana Galimberti, Samantha Dicuonzo, M.C. Leonardi, Sabrina Kahler-Ribeiro-Fontana, F. Colombo, Roberto Orecchia, Barbara Alicja Jereczek-Fossa, Mattia Zaffaroni, and E. La Rocca

Subjects
Oncology, medicine.medical_specialty, Breast cancer, business.industry, medicine.medical_treatment, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Hematology, business, medicine.disease, Neoadjuvant therapy
Published
2021
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2. PO-1606 Comparing TomoHelical and TomoDirect in postmastectomy hypofractionated RT after IBR

Author

Marianna Alessandra Gerardi, Samuele Frassoni, Barbara Alicja Jereczek-Fossa, Samantha Dicuonzo, M.C. Leonardi, P. Veronesi, R. Luraschi, Mattia Zaffaroni, Cristiana Fodor, Federica Cattani, Vincenzo Bagnardi, M.A. Zerella, F. Emiro, Roberto Orecchia, Viviana Galimberti, F. Patti, Anna Morra, and Damaris Patricia Rojas

Subjects
Oncology, Radiology, Nuclear Medicine and imaging, Hematology
Published
2021
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5. PO-1190 Machine learning to predict locoregional relapse in pT1-2pN0-1 breast cancer following mastectomy

Author

S. Volpe, F. Bellerba, M. Zaffaroni, M. Pepa, L.J. Isaksson, G. Maimone, B. Menzani, I. Monaco, P. Maisonneuve, I.R. Scognamiglio, S. Dicuonzo, M.A. Zerella, D.P. Rojas, G. Marvaso, C. Fodor, S. Gandini, E. De Momi, P. Veronesi, G. Corso, V.E. Galimberti, M.C. Leonardi, and B.A. Jereczek-Fossa

Subjects
Oncology, Radiology, Nuclear Medicine and imaging, Hematology
Published
2022
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6. PO-1569 An international, multicenter planning study on regional nodal irradiation in breast cancer

Author

M.N. Duma, B. Vrou Offersen, M. Bessermann Johansen, K. Boye, B.S. Kristensen, I. Meattini, L. Marrazzo, V. Di Cataldo, A. De Caluwé, D. Teixeira, P. Franco, G. Loi, I. Jensen, M. Møller, K. Verhoeven, R. Marseguerra, K. Legård Jakobsen, S. Aziz-Jowad Al-Rawi, Y. Kirova, B.A. Jereczek-Fossa, M.C. Leonardi, R. Luraschi, I. Kindts, L. Goethals, P. Loap, J. Vu-Bezim, S. Weimann, T. Teichmann, and A. Wittig

Subjects
Oncology, Radiology, Nuclear Medicine and imaging, Hematology
Published
2022
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7. PH-0604 Hippocampal Sparing WBRT: Trade-Off Between Tumor Control And Quality Of Life? A series of 150 pts

Author

Luca Bergamaschi, Gaia Piperno, Giulia Marvaso, F. Emiro, Barbara Alicja Jereczek-Fossa, Matteo Pepa, I. Cavallo, M.C. Leonardi, Giulia Corrao, Giulia Riva, Federica Cattani, V.E. Pierini, Sara Gandini, Mattia Zaffaroni, Roberto Orecchia, and Annamaria Ferrari

Subjects
Oncology, medicine.medical_specialty, Series (stratigraphy), Quality of life, business.industry, Internal medicine, Medicine, Radiology, Nuclear Medicine and imaging, Hematology, Hippocampal formation, business, Tumor control
Published
2021
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8. PO-1097 Preclinical evaluation for dose escalation in the preoperative SBRT of early breast cancer

Author

Elena Rondi, Roberto Orecchia, P. Veronesi, Viviana Galimberti, Federica Cattani, M.C. Leonardi, Annamaria Ferrari, M.A. Zerella, Barbara Alicja Jereczek-Fossa, C. Piccolo, and S. Vigorito

Subjects
Oncology, medicine.medical_specialty, business.industry, Internal medicine, medicine, Dose escalation, Radiology, Nuclear Medicine and imaging, Hematology, business, Early breast cancer
Published
2021
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9. PH-0219 Ten-year results of hypofractionated whole breast RT and intraoperative boost in premenopausal women

Author

P. Veronesi, Samantha Dicuonzo, Anna Morra, M.C. Leonardi, Viviana Galimberti, C. Cormio, M.A. Zerella, Barbara Alicja Jereczek-Fossa, Damaris Patricia Rojas, Mattia Zaffaroni, Federica Cattani, Cristiana Fodor, and Roberto Orecchia

Subjects
medicine.medical_specialty, Oncology, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, Whole breast, business
Published
2021
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10. PD-0295: FAST approach in early breast cancer irradiation: toxicity and outcome in a 3DCRT vs IMRT comparison

Author

Roberto Orecchia, Luca Bergamaschi, Viviana Galimberti, Barbara Alicja Jereczek-Fossa, Veronica Dell’Acqua, Cristiana Fodor, Samantha Dicuonzo, M.A. Zerella, Anna Morra, S. Arculeo, Federica Cattani, Samuele Frassoni, Vincenzo Bagnardi, M.C. Leonardi, P. Veronesi, and Marianna Alessandra Gerardi

Subjects
Oncology, medicine.medical_specialty, business.industry, Internal medicine, Toxicity, medicine, Radiology, Nuclear Medicine and imaging, Hematology, business, Outcome (game theory), Early breast cancer
Published
2020
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11. PO-0937: Partial breast re-irradiation with IMRT for local recurrence after whole breast radiotherapy

Author

Samantha Dicuonzo, Viviana Galimberti, Cristiana Fodor, Anna Morra, F. Pansini, Roberto Orecchia, S. Arculeo, Barbara Alicja Jereczek-Fossa, P. Veronesi, Stefania Comi, I. Cavallo, Samuele Frassoni, M.C. Leonardi, Vincenzo Bagnardi, Federica Cattani, Veronica Dell’Acqua, and Marianna Alessandra Gerardi

Subjects
Re-Irradiation, medicine.medical_specialty, Oncology, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, business, Whole breast radiotherapy, Partial breast
Published
2020
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12. PO-0979: Variability of axillary nodal CTV contouring in breast cancer (PART I - geometric evaluation)

Author

Matteo Pepa, M.C. Leonardi, S. Vigorito, R. Luraschi, Federica Cattani, Delia Ciardo, Simone Giovanni Gugliandolo, Roberto Orecchia, and Barbara Alicja Jereczek-Fossa

Subjects
medicine.medical_specialty, Contouring, Breast cancer, Oncology, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, medicine.disease, business, NODAL
Published
2020
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13. PO-0981: Variability of axillary nodal CTV contouring in breast cancer (PART II – dosimetric impact)

Author

Federica Cattani, Roberto Orecchia, M.C. Leonardi, R. Luraschi, Simone Giovanni Gugliandolo, Matteo Pepa, S. Vigorito, Delia Ciardo, and Barbara Alicja Jereczek-Fossa

Subjects
Contouring, medicine.medical_specialty, Breast cancer, Oncology, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, business, NODAL, medicine.disease
Published
2020
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14. EP-1311 POLO concept: salvage whole breast radiotherapy with Tomotherapy after intraoperative radiotherapy

Author

Giulia Riva, A. Casbarra, Cristiana Fodor, E. Miglietta, A.M. Camarda, Roberto Orecchia, Barbara Alicja Jereczek-Fossa, Anna Morra, Samantha Dicuonzo, M.C. Leonardi, and Marianna Alessandra Gerardi

Subjects
medicine.medical_specialty, Oncology, business.industry, medicine.medical_treatment, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, business, Intraoperative radiotherapy, Whole breast radiotherapy, Tomotherapy
Published
2019
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15. EP-1310 Toxicity evaluation of a hypofractionated WBRT with SIB for breast cancer using TomoDirect

Author

Alessia Surgo, Veronica Dell’Acqua, Barbara Alicja Jereczek-Fossa, M.C. Leonardi, Samantha Dicuonzo, Roberto Orecchia, F. Pansini, R. Luraschi, Cristiana Fodor, P. Veronesi, Federica Cattani, Sara Raimondi, Damaris Patricia Rojas, Anna Morra, Marianna Alessandra Gerardi, and E. Miglietta

Subjects
Oncology, medicine.medical_specialty, Breast cancer, business.industry, Internal medicine, Toxicity, medicine, Radiology, Nuclear Medicine and imaging, Hematology, medicine.disease, business
Published
2019
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16. PO-0819 Stereotactic Radiation Therapy in Oligometastatic Colorectal Cancer: 102 patients and 150 lesions

Author

F. Pansini, M.C. Leonardi, Cristiana Fodor, Veronica Dell’Acqua, B.A. Jereczek Fossa, Alessia Surgo, Jarek Kobiela, F. Kraja Pupuleku, S. Vigorito, Delia Ciardo, Piotr Spychalski, Federica Cattani, M.A. Zerella, and C. Francia

Subjects
medicine.medical_specialty, Oncology, Colorectal cancer, business.industry, medicine.medical_treatment, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Stereotactic radiation therapy, Radiology, medicine.disease, business
Published
2019
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17. EP-1326: Hypofractionated IMRT using Tomotherapy for early stage breast cancer: early chronic toxicity

Author

S. Arculeo, R. Luraschi, Marianna Alessandra Gerardi, Roberto Orecchia, Federica Cattani, Rosalinda Ricotti, Samantha Dicuonzo, Damaris Patricia Rojas, P. Veronesi, Veronica Dell’Acqua, Alessia Surgo, R. Spoto, Anna Morra, B. Jereczek, Cristiana Fodor, A. Casbarra, Sara Raimondi, and M.C. Leonardi

Subjects
Oncology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Hematology, medicine.disease, Tomotherapy, Breast cancer, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Stage (cooking), business, Chronic toxicity
Published
2018
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18. SP-0653: Hypofractionation for breast cancer: 30, 15 or 5 fractions?

Author

S. Arculeo, Samantha Dicuonzo, A. Casbarra, Damaris Patricia Rojas, Alessia Surgo, B.A. Jereczek Fossa, M.C. Leonardi, R. Spoto, Marianna Alessandra Gerardi, Anna Morra, C. Arrobbio, Veronica Dell’Acqua, Federica Cattani, and Roberto Orecchia

Subjects
Oncology, medicine.medical_specialty, Breast cancer, business.industry, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Hematology, medicine.disease, business
Published
2018
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19. EP-1344: Long-term reconstruction failure after postmastectomy RT to temporary expander or permanent implant

Author

Roberto Orecchia, F. De Lorenzi, Cristiana Fodor, Marianna Alessandra Gerardi, Davide Radice, Samantha Dicuonzo, Alessia Surgo, Barbara Alicja Jereczek-Fossa, Anna Morra, Damaris Patricia Rojas, Veronica Dell’Acqua, Raffaella Cambria, Viviana Galimberti, Federica Cattani, and M.C. Leonardi

Subjects
medicine.medical_specialty, Permanent implant, Oncology, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, business, Surgery, Term (time)
Published
2018
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20. EP-1212 Clinical outcome in brain metastases from breast cancer treated with stereotactic radiotherapy

Author

Barbara Alicja Jereczek-Fossa, S. Vigorito, Elena Rondi, Delia Ciardo, Roberto Orecchia, S. Durante, Giulia Riva, Gaia Piperno, M.C. Leonardi, and Annamaria Ferrari

Subjects
Stereotactic radiotherapy, medicine.medical_specialty, Breast cancer, Oncology, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, medicine.disease, business, Outcome (game theory)
Published
2019
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21. EP-1596: Intraoperative radiotherapy with electrons in breast cancer patients with cardiac devices

Author

Elena Rondi, A. Bazani, R. Luraschi, M.C. Leonardi, Federica Cattani, Viviana Galimberti, Nicoletta Colombo, Roberta Lazzari, Barbara Alicja Jereczek-Fossa, and Giovanni Corso

Subjects
Oncology, medicine.medical_specialty, business.industry, fungi, food and beverages, Hematology, medicine.disease, Breast cancer, Radiology Nuclear Medicine and imaging, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Radiology, business, Intraoperative radiotherapy
Published
2016
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22. EP-1704: Breast tumour bed contouring: influence of surgical clips assessed on the same imaging

Author

Federica Cattani, Roberto Orecchia, Giuseppe Fanetti, Rosalinda Ricotti, Samantha Dicuonzo, Veronica Dell’Acqua, Barbara Alicja Jereczek-Fossa, Guido Baroni, Anna Morra, M.C. Leonardi, Raffaella Cambria, Delia Ciardo, and D. Damaris

Subjects
Contouring, medicine.medical_specialty, Oncology, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Radiology, business, Surgical Clips
Published
2017
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23. PO-0840: Hypofractionated intensity modulated radiotherapy in patients with immediate breast reconstruction

Author

Barbara Alicja Jereczek-Fossa, Federica Cattani, Cristiana Fodor, Rosalinda Ricotti, Raffaella Cambria, Viviana Galimberti, A. Viola, Veronica Dell’Acqua, Delia Ciardo, Samantha Dicuonzo, Roberto Orecchia, Anna Morra, R. Luraschi, M.C. Leonardi, and Damaris Patricia Rojas

Subjects
medicine.medical_specialty, Oncology, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, In patient, Hematology, Radiology, Intensity modulated radiotherapy, business, Breast reconstruction
Published
2017
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24. PO-0660: Partial breast re-irradiation with IMRT in patients with local failure after conservative treatment

Author

Samantha Dicuonzo, Matteo Augugliaro, Viviana Galimberti, Roberto Orecchia, Federica Cattani, Alessia Surgo, Veronica Dell’Acqua, F. Pansini, R. Spoto, A. Viola, Anna Morra, Barbara Alicja Jereczek-Fossa, and M.C. Leonardi

Subjects
Re-Irradiation, Conservative treatment, medicine.medical_specialty, Oncology, business.industry, Medicine, Local failure, Radiology, Nuclear Medicine and imaging, In patient, Hematology, Radiology, business, Partial breast
Published
2017
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25. EP-1323: Dosimetry results and toxicity of a 3-week schedule RT with SIB in breast cancer, with TomoDirect

Author

F. Patti, Barbara Alicja Jereczek-Fossa, A. Viola, Matteo Augugliaro, Veronica Dell’Acqua, Samantha Dicuonzo, Sara Raimondi, Rosalinda Ricotti, M.C. Leonardi, Marianna Alessandra Gerardi, S. Arculeo, C. Arrobbio, Roberto Orecchia, Damaris Patricia Rojas, Anna Morra, F. Emiro, Cristiana Fodor, Federica Cattani, and Viviana Galimberti

Subjects
Oncology, Schedule, medicine.medical_specialty, business.industry, Hematology, medicine.disease, Breast cancer, Internal medicine, Toxicity, Medicine, Dosimetry, Radiology, Nuclear Medicine and imaging, business
Published
2018
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26. EP-1753: Intrafraction setup variability for breast Helical Tomotherapy

Author

Anna Morra, Chiara Gianoli, Barbara Alicja Jereczek-Fossa, Roberto Orecchia, Marco Riboldi, Guido Baroni, Rosalinda Ricotti, F. Pansini, M.C. Leonardi, Federica Cattani, Raffaella Cambria, Delia Ciardo, and Giovanni Fattori

Subjects
Oncology, business.industry, Radiology Nuclear Medicine and imaging, medicine.medical_treatment, medicine, Radiology, Nuclear Medicine and imaging, Hematology, Nuclear medicine, business, Tomotherapy
Published
2016
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27. PO-0661: Intraoperative partial breast re-irradiation: a multicenter study of the AIRO IORT Working Group

Author

M.C. Leonardi, G.B. Ivaldi, M. Alessandro, G. Catalano, A. Ciabattoni, C. Fillini, M. Guenzi, L. Tomio, D.P. Rojas, M. Augugliaro, C. Fodor, C. Sangalli, F. Rossetto, B.A. Jereczek-Fossa, R. Orecchia, and null AIRO IORT Working Group

Subjects
Re-Irradiation, medicine.medical_specialty, Oncology, Multicenter study, business.industry, medicine, Radiology, Nuclear Medicine and imaging, Hematology, business, Partial breast, Surgery
Published
2017
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28. PV-0237: Management and outcome of local failure after intraoperative partial breast irradiation

Author

M.C. Leonardi, L. Tomio, G.B. Ivaldi, G. Catalano, M. Alessandro, C. Fillini, A. Ciabattoni, M. Guenzi, C.M. Francia, C. Fodor, F. Rossetto, B.A. Jereczek-Fossa, R. Orecchia, and null AIRO IORT Working Group

Subjects
medicine.medical_specialty, Oncology, business.industry, medicine, Partial Breast Irradiation, Local failure, Radiology, Nuclear Medicine and imaging, Hematology, business, Outcome (game theory), Surgery
Published
2017
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29. EP-1191: Postmastectomy locoregional irradiation to temporary tissue-expander or permanent breast implant

Author

P. Veronesi, M. Rietjens, Rosalinda Ricotti, C. Francia, Cristiana Fodor, Anna Morra, M.C. Leonardi, Damaris Patricia Rojas, Roberto Orecchia, Veronica Dell’Acqua, R. Luraschi, Barbara Alicja Jereczek-Fossa, F. De Lorenzi, Giulia Riva, Federica Cattani, Marianna Alessandra Gerardi, Raffaella Cambria, and Delia Ciardo

Subjects
Tissue expander, Oncology, business.industry, law, Breast implant, Medicine, Radiology, Nuclear Medicine and imaging, Hematology, Irradiation, business, Nuclear medicine, law.invention
Published
2017
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30. EP-1494: Evaluation of intra-fraction breathing pattern variability in Helical Tomotherapy by means of optical tracking

Author

B. Jereczek, Guido Baroni, Roberto Orecchia, Delia Ciardo, Rosalinda Ricotti, F. Pansini, M.C. Leonardi, Marco Riboldi, Federica Cattani, Anna Morra, and Giovanni Fattori

Subjects
Physics, medicine.medical_specialty, medicine.medical_treatment, Hematology, Tomotherapy, Optical tracking, Breathing pattern, Oncology, Radiology Nuclear Medicine and imaging, medicine, Radiology, Nuclear Medicine and imaging, Fraction (mathematics), Radiology, Biomedical engineering
Published
2015
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32. EP-1190: Anticipated boost with IORT followed by hypofractionated wholebreast radiotherapy (AFTEREIGHT phase II study)

Author

B. Jereczek, F. Pansini, Raffaella Cambria, Cristiana Fodor, Samantha Dicuonzo, M.C. Leonardi, R. Luraschi, Veronica Dell’Acqua, Roberto Orecchia, and Anna Morra

Subjects
Radiation therapy, Oncology, business.industry, medicine.medical_treatment, Medicine, Phases of clinical research, Radiology, Nuclear Medicine and imaging, Hematology, business, Nuclear medicine
Published
2014
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33. PO-1005: Partial breast re-irradiation using brachytherapy for local recurrences after prior external beam radiotherapy

Author

Stefania Comi, Federica Cattani, Anna Morra, Cristiana Fodor, Roberta Lazzari, Barbara Alicja Jereczek-Fossa, M.C. Leonardi, Roberto Orecchia, Andrea Vavassori, and Federica Gherardi

Subjects
Re-Irradiation, Oncology, business.industry, medicine.medical_treatment, Brachytherapy, Medicine, Radiology, Nuclear Medicine and imaging, Hematology, External beam radiotherapy, business, Nuclear medicine, Radiation treatment planning, Partial breast
Published
2014
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34. EP-1880: Inter-observer variability in contouring of the tumor bed in breast cancer patients with and without clips

Author

Federica Cattani, Veronica Dell’Acqua, Raffaella Cambria, Delia Ciardo, Anna Morra, Samantha Dicuonzo, Barbara Alicja Jereczek-Fossa, M.C. Leonardi, Roberto Orecchia, and Guido Baroni

Subjects
medicine.medical_specialty, Contouring, business.industry, Hematology, medicine.disease, Surgery, Breast cancer, Oncology, medicine, Radiology, Nuclear Medicine and imaging, Tumor bed, Radiology, CLIPS, Observer variation, business, computer, computer.programming_language
Published
2014
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35. PO-0811: From 3D conformal to TomoDirect™ modality treatment for the postoperative breast radiotherapy

Author

R. Luraschi, M.C. Leonardi, Federica Cattani, Raffaella Cambria, Anna Morra, Roberto Orecchia, Guido Pedroli, and Stefania Russo

Subjects
Modality (human–computer interaction), Oncology, Radiology Nuclear Medicine and imaging, business.industry, Medicine, Radiology, Nuclear Medicine and imaging, Breast radiotherapy, Hematology, Conformal radiation, business, Radiation treatment planning, Nuclear medicine
Published
2013
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39. 1063 poster NEOADJUVANT VOLUMETRIC MODULATED ARC THERAPY FOR RECTAL CANCER: ANALYSIS OF ACUTE TOXICITY DATA OF 16 PATIENTS

Author

Cristiana Fodor, Elena Rondi, R. Mauro, Barbara Alicja Jereczek-Fossa, Roberto Orecchia, Andrea Vavassori, Roberta Lazzari, M.C. Leonardi, Federica Cattani, P. Porcu, Agnese Cecconi, and S. Vigorito

Subjects
Oncology, medicine.medical_specialty, Colorectal cancer, business.industry, Internal medicine, medicine, Radiology, Nuclear Medicine and imaging, Hematology, medicine.disease, business, Volumetric modulated arc therapy, Acute toxicity
Published
2011
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40. 8 poster FOUR YEAR RESULTS OF ELECTRON INTRAOPERATIVE BOOST AND HYPOFRACTIONATED EXTERNAL BEAM RADIOTHERAPY AFTER BREAST-CONSERVING SURGERY IN PREMENOPAUSAL WOMEN

Author

Anna Morra, Cristiana Fodor, Umberto Veronesi, Roberta Lazzari, Annamaria Ferrari, Roberto Orecchia, Barbara Alicja Jereczek-Fossa, M.C. Leonardi, and Giovanni Ivaldi

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Incidence (epidemiology), ECOG Performance Status, Hematology, medicine.disease, law.invention, Surgery, Breast cancer, Oncology, Randomized controlled trial, law, medicine, Breast-conserving surgery, Radiology, Nuclear Medicine and imaging, External beam radiotherapy, Stage (cooking), business, Mastectomy
Abstract

Materials: From April 1999 to March 2010 IORT given as boost in early breast cancer patients has been carried on at San Filippo Neri Hospital in Rome. A total of 278 patients up to 75 years (range 29-75), I◦ and II◦ stage breast cancer and ECOG performance status < 2, were treated with an anticipated boost dose of 10 Gy to PTV (tumour volume with a radial margin of 1 to 2 centimetres). The boost was delivered with a movable Linac NOVAC7. All the patients received additional 45-50 Gy of external radiotherapy in 18-25 fractions to the whole breast. One hundred and twenty six patients were included in a randomized trial carried on from April 1999 to December 2004 of IORT versus external beam boost The valuation of acute and late toxicity was performed using WHO scale and the aesthetic result was assessed. Results: The median follow-up was 82,7 months (range 2-138 months).Seventy eight patients (28%) were women younger than 45 years. Two local recurrence were observed: one (true local recurrence) presented in a 62 years old patient with a ductal infiltrating carcinoma staged as pT1bN0Mx, G2, after 100 months follow up and the other (marginal recurrence) in a 56 yearss old patient with a ductal infiltrating carcinoma staged as pT1cN0Mx, G3, at 112 months follow up. No local failures were observed in the group of young women. As acute toxicity 22 patients developed post-surgical seromas and 7 wound healing problems occurred (6,8%). No late complications associated with IORT were observed, but three cases of liponecrosis in the treatment area. In 7 patients, a secondary mastectomy was performed for tumour multicentricity or excessive intraductal component. Cosmetic result was very good (objective valuation 92,3% good or excellent, subjective valuation 88,7%) and comparable to patients treated with external boost (87,4% good or excellent). The overall DFS was 88,7%, 23 patients developed distant metastasis and 12 died (nine of them for disease). Six patients were lost at the follow up Conclusions: Our data suggest that IORT as anticipated boost after breastconserving surgery is a reliable alternative to conventional postoperative fractionated boost, particularly in younger women, for whom published studies indicate higher risk of local recurrence. The incidence of recurrence with the IORT boost, for any age, including young women, is quite low.Further research is required to clarify several issues such as identification of the most appropriate subgroups of patients for IORT as boost or complete replacement of postoperative radiotherapy.

Published
2011
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41. PO-0687: Technical feasibility of whole breast radiotherapy for local relapse after a previous partial breast irradiation

Author

Federica Cattani, Roberto Orecchia, Marianna Alessandra Gerardi, Cristiana Fodor, Barbara Alicja Jereczek-Fossa, R. Luraschi, M.C. Leonardi, Anna Morra, Veronica Dell’Acqua, and Raffaella Cambria

Subjects
medicine.medical_specialty, Technical feasibility, Oncology, business.industry, Radiology Nuclear Medicine and imaging, medicine, Partial Breast Irradiation, Radiology, Nuclear Medicine and imaging, Radiology, Hematology, business, Whole breast radiotherapy
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