1. Primary lymphoepithelial carcinoma of the parotid gland in a North African woman
- Author
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Soumaya Rammeh, Amel Trabelsi, Atef Ben Abdelkader, Soumaya Ben Abdelkrim, Badreddine Sriha, Faten Hammedi, and Monia Omezzine
- Subjects
Pathology ,medicine.medical_specialty ,Histology ,Case Report ,Malignancy ,lcsh:RC254-282 ,Pleomorphic adenoma ,Pathogenesis ,stomatognathic system ,pathology ,Lymphoepithelial carcinoma, parotid, pathology ,medicine ,Neoplasm ,Frozen section procedure ,business.industry ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,medicine.disease ,Parotid gland ,Parotid Region ,stomatognathic diseases ,medicine.anatomical_structure ,Oncology ,Nasopharyngeal carcinoma ,parotid ,lymphoepithelial carcinoma ,business - Abstract
Lymphoepithelial carcinoma of the salivary glands is a rare neoplasm that is characterized by a non-neoplastic lymphocytic infiltration associated with an epithelial proliferation. It involves mainly the parotid gland. Racial and geographical factors contribute to the pathogenesis of this tumor. We report a case of a 70-year old woman from a non-endemic area who presented with several months history of swelling in the parotid region. Magnetic resonance imaging showed a parotid mass suggestive of a pleomorphic adenoma. The diagnosis of lymphoepithelial carcinoma of the parotid gland was performed on the surgical specimen. A primitive nasopharyngeal carcinoma was ruled out by random biopsies of the nasopharynx mucosa. The Epstein-Barr virus (EBV) was absent in neoplastic cells. We insist that, even in non-endemic areas and when clinical and radiological characteristics are not suggestive of malignancy, intra-operative frozen section analysis should be used in order to ensure the appropriate treatment.
- Published
- 2009