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B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event A transgender man (female-to-male transsexual) in his 20s [ I exact age not stated i ] developed spontaneous leak of cerebrospinal fluid (CSF) secondary to idiopathic intracranial hypertension (IIH) following treatment with testosterone cipionate as gender reassignment therapy. The patient declined repeat lumbar puncture for measurement of CSF opening pressure. The patient was hospitalised and underwent expanded endonasal surgery for CSF leak repair. [Extracted from the article]

B Author Information b An event is serious (based on the ICH definition) when the patient outcome is: * death * life-threatening * hospitalisation * disability * congenital anomaly * other medically important event A 64-year-old man developed demyelinating peripheral neuropathy with cranial neuropathy during treatment with ipilimumab and nivolumab for advanced melanoma. Nerve conduction studies for the posterior tibial nerve and right ulnar nerve showed prolonged distal latency, decreased conduction velocity and conduction block, indicating demyelinating neuropathy. Eventually, he was diagnosed with immune-related demyelinating peripheral neuropathy with cranial neuropathy. [Extracted from the article]