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Start Over Author "Maas, Coen" Journal research and practice in thrombosis and haemostasis
5 results on '"Maas, Coen"'

1. Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis

Author

Bergmeier, Wolfgang, Antoniak, Silvio, Conway, Edward M, Denis, Cécile V, George, Lindsey A, Isermann, Berend, Key, Nigel S, Krishnaswamy, Sriram, Lam, Wilbur A, Lillicrap, David, Liu, Jian, Looney, Mark R, López, José A, Maas, Coen, Peyvandi, Flora, Ruf, Wolfram, Sood, Anil K, Versteeg, Henri H, Wolberg, Alisa S, Wong, Pancras C, Wood, Jeremy P, and Weiler, Hartmut

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

This 9th Symposium on Hemostasis is an international scientific meeting held biannually in Chapel Hill, North Carolina. The meeting is in large measure the result of the close friendship between the late Dr. Harold R. Roberts of UNC Chapel Hill and Dr. Ulla Hedner of Novo Nordisk. When Novo Nordisk was developing the hemophilia therapy that would become NovoSeven, they sponsored a series of meetings to understand the basic biology and clinical applications of factor VIIa. The first meeting in Chapel Hill was held April 4-6, 2002 with Dr. Roberts as the organizer. Over the years, the conference emphasis has expanded from discussions of factor VIIa and tissue factor to additional topics in hemostasis and thrombosis. This year's meeting includes presentations by internationally renowned speakers that discuss the state-of-the-art on an array of important topics, including von Willebrand factor, engineering advances, coagulation and disease, tissue factor biology, therapeutic advances, and basic clotting factor biology. Included in this review article are illustrated abstracts provided by our speakers, which highlight the main conclusions of each invited talk. This will be the first meeting without Dr. Roberts in attendance, yet his commitment to excellent science and his focus on turning science to patient care are pervasively reflected in the presentations by our speakers.

Published
2018

2. Illustrated State‐of‐the‐Art Capsules of the ISTH 2021 Congress

Author

Krishnaswamy, Sriram, Ageno, Walter, Arabi, Yaseen, Barbui, Tiziano, Cannegieter, Suzanne, Carrier, Marc, Cleuren, Audrey C., Collins, Peter, Panicot‐Dubois, Laurence, Freedman, Jane E., Freson, Kathleen, Hogg, Philip, James, Andra H., Kretz, Colin A., Lavin, Michelle, Leebeek, Frank W.G., Li, Weikai, Maas, Coen, Machlus, Kellie, Makris, Michael, Martinelli, Ida, Medved, Leonid, Neerman‐Arbez, Marguerite, O’Donnell, James S., O'Sullivan, Jamie, Rajpurkar, Madhvi, Schroeder, Verena, Spiegel, Paul Clinton, Jr, Stanworth, Simon J., Green, Laura, and Undas, Anetta

Published
2021
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4. Illustrated State‐of‐the‐Art Capsules of the ISTH 2019 Congress in Melbourne, Australia

Author

Ward, Christopher M., Andrews, Robert K., Barco, Stefano, Battinelli, E.M., Boilard, Eric, Bos, Mettine H.A., Chicanne, G., Chuansumrit, Ampaiwan, Conway, Edward M., Curry, N., Cutler, Daniel, Danese, Elisa, De Meyer, Simon F., Del Rio, Jose M., Despotovic, Jenny, Di Paola, Jorge, Eikelboom, John, Emsley, Jonas, Eto, Koji, Fijnvandraat, Karin, Flaumenhaft, Robert, Flick, Matthew, Fuchs, Tobias A., Gomez, Keith, Goto, Shinya, Hamilton, Justin R., Hitchcock, Ian S., Jenne, Craig N., Johnsen, Jill M., Ju, Lining A., Le Gal, Grégoire, Levade, M., Lip, Gregory Y.H., Luyendyk, Jim, Maas, Coen, Magnusson, Maria, Mangin, Pierre, Mast, Alan, McLintock, Claire, Miranda, Sébastien, Nathwani, Amit, Ni, Heyu, Áinle, Fionnuala N., Nilsson, Susie, Ny, Tor, O’Brien, Sarah H., O’Donnell, James S., Payrastre, B., Peter, Karlheinz, Rak, Janusz, Randi, Anna M., Rauova, Lubica, Reinhardt, Christoph, Rodger, Marc, Rondina, Matthew, Schreiber, Karen, Severin, S., Shima, Midori, Spyropoulos, Alex, Stanworth, S.J., Suzuki‐Inoue, Katsue, Thomas, Moumneh, Tsukiji, Nagaharu, Urano, Tetsumei, Valet, C., Vanhoorelbeke, Karen, Verhamme, Peter, Weitz, Jeffrey, Wolberg, Alisa, Zentner, Dominica, and Zhu, Cheng

Published
2019
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5. Lupus anticoagulant associates with thrombosis in patients with COVID-19 admitted to intensive care units

Author

Noordermeer, Tessa, Schutgens, Roger E. G., Visser, Chantal, Rademaker, Emma, de Maat, Moniek P. M., Jansen, A. J. Gerard, Limper, Maarten, Cremer, Olaf L., Kruip, Marieke J. H. A., Endeman, Henrik, Maas, Coen, de Laat, Bas, Urbanus, Rolf T., van de Beek, D., Brouwer, M. C., de Bruin, S., Coppens, M., van Es, N., van Haaps, T. F., Juffermans, N. P., Muller, M. C. A., Vlaar, A. P. J., Hertogh, C. M. P. M., Heunks, L. M. A., Hugtenburg, J. G., van Kooten, J., Nossent, E. J., Smulders, Y., Tuinman, P. R., Noordegraaf, A. Vonk, Grootenboers, M. J. J. H., van Guldener, C., Kant, M., Lansbergen, A., Faber, J., Hajer, G., Stemerdink, A., van den Akker, J., Bierings, R., Endeman, H., Goeijenbier, M., Hunfeld, N. G. M., van Gorp, E. C. M., Gommers, D. A. M. P. J., Koopmans, M. P. G., Kruip, M. J. H. A., Kuiken, T., Langerak, T., Leebeek, Lauw, M. N., de Maat, M. P. M., Noack, D., Paats, M. S., Raadsen, M. P., Rockx, B., Rokx, C., Schurink, C. A. M., Tong-Minh, K., van den Toorn, L., den Uil, C. A., Visser, C., Boutkourt, F., Roest, T., Douma, R. A., de Haan, L. R., ten Wolde, M., Bemelmans, R. H. H., Festen, B., Stads, S., de Jager, C. P. C., Simons, K. S., Antoni, M. L., Bos, M. H., Burggraaf, J. L. I., Cannegieter, S. C., Eikenboom, H. C. J., den Exter, P. L., Geelhoed, J. J. M., Huisman, M. V., de Jonge, E., Kaptein, F. H. J., Klok, F. A., Kroft, L. J. M., Lijfering, W. M., Nab, L., Ninaber, M. K., Putter, H., Ramai, S. R. S., da Rocha Rondon, A. M., Roukens, A. H. E., Stals, M. A. M., Versteeg, H. H., Vliegen, H. W., van Vlijmen, B. J. M., van de Berg, T., Bruggemann, R., van Bussel, B. C. T., ten Cate, H., ten Cate-Hoek, A., Hackeng, T. M., Henskens, ir. Y., Hulshof, A., Mulder, M., Olie, R. H., Schurgers, L., Spaetgens, B., Spronk, H., Spruit, M. A., Winckers, K., Nieuwenhuizen, L., Franken, B., Schrover, I. M., de Waal, E. G. M., Beishuizen, A., Cornet, A., Krabbe, J., Kramers, K., Leentjens, J., de Mast, Q., Middeldorp, S., Brouwer, R. E., Ellerbroek, J. L. J., Tijmensen, J., Hovens, M. M. C., Oostdijk, E. A. N., Westerhof, B. D., Faber, L. M., van den Biggelaar, M., Meijers, J. C. M., Voorberg, J., Kevenaar, M. E., Soei, Y. L., Wils, E. J., Croles, F. N., de Laat, B., Kamphuisen, P. W., Vink, R., Lisman, T., Meijer, K., van Tichelaar, Y. I. G., Cremer, O. L., Geersing, G., Kaasjager, H. A. H., Kusadasi, N., Huisman, A., Maas, C., Nijkeuter, M., Schutgens, R. E. G., Creveldkliniek, Van, Urbanus, R. T., Westerink, J., Faber, H. J., Koster, S. C. E., van Montfort, P., van Twist, D. J. L., RS: Carim - B01 Blood proteins & engineering, Biochemie, Hematology, Intensive Care, Neurology, ANS - Neuroinfection & -inflammation, Intensive Care Medicine, ACS - Pulmonary hypertension & thrombosis, AII - Inflammatory diseases, Vascular Medicine, ACS - Amsterdam Cardiovascular Sciences, Graduate School, ACS - Microcirculation, Medical Microbiology and Infection Prevention, ARD - Amsterdam Reproduction and Development, Experimental Vascular Medicine, Landsteiner Laboratory, ACS - Atherosclerosis & ischemic syndromes, Elderly care medicine, APH - Aging & Later Life, Clinical pharmacology and pharmacy, APH - Health Behaviors & Chronic Diseases, Pulmonary medicine, Internal medicine, ACS - Diabetes & metabolism, Intensive care medicine, General practice, and Amsterdam Gastroenterology Endocrinology Metabolism

Subjects
lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], lupus anticoagulant, risk factor, critically ill, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], COVID-19, Hematology, thrombosis, Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]
Abstract

Contains fulltext : 286889.pdf (Publisher’s version ) (Open Access) BACKGROUND: Thrombosis is a frequent and severe complication in patients with coronavirus disease 2019 (COVID-19) admitted to the intensive care unit (ICU). Lupus anticoagulant (LA) is a strong acquired risk factor for thrombosis in various diseases and is frequently observed in patients with COVID-19. Whether LA is associated with thrombosis in patients with severe COVID-19 is currently unclear. OBJECTIVE: To investigate if LA is associated with thrombosis in critically ill patients with COVID-19. PATIENTS/METHODS: The presence of LA and other antiphospholipid antibodies was assessed in patients with COVID-19 admitted to the ICU. LA was determined with dilute Russell's viper venom time (dRVVT) and LA-sensitive activated partial thromboplastin time (aPTT) reagents. RESULTS: Of 169 patients with COVID-19, 116 (69%) tested positive for at least one antiphospholipid antibody upon admission to the ICU. Forty (24%) patients tested positive for LA; of whom 29 (17%) tested positive with a dRVVT, 19 (11%) tested positive with an LA-sensitive aPTT, and 8 (5%) tested positive on both tests. Fifty-eight (34%) patients developed thrombosis after ICU admission. The odds ratio (OR) for thrombosis in patients with LA based on a dRVVT was 2.5 (95% confidence interval [CI], 1.1-5.7), which increased to 4.5 (95% CI, 1.4-14.3) in patients at or below the median age in this study (64 years). LA positivity based on a dRVVT or LA-sensitive aPTT was only associated with thrombosis in patients aged less than 65 years (OR, 3.8; 95% CI, 1.3-11.4) and disappeared after adjustment for C-reactive protein. CONCLUSION: Lupus anticoagulant on admission is strongly associated with thrombosis in critically ill patients with COVID-19, especially in patients aged less than 65 years.

Published
2022
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