8 results on '"Giuseppe Liistro"'
Search Results
2. Chest Expansion and Lung Function for Healthy Subjects and Individuals With Pulmonary Disease
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Gregory Reychler, Stéphanie Lefebvre, Giuseppe Liistro, Marion Derasse, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, and UCL - (SLuc) Service de pneumologie
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Adult ,Lung Diseases ,Male ,Pulmonary and Respiratory Medicine ,Thorax ,Spirometry ,medicine.medical_specialty ,respiratory mechanics ,assessment ,Respiratory physiology ,Critical Care and Intensive Care Medicine ,03 medical and health sciences ,FEV1/FVC ratio ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Lung volumes ,Thoracic Wall ,Lung ,Original Research ,thorax ,Rib cage ,medicine.diagnostic_test ,chest wall mobility ,business.industry ,lung function ,General Medicine ,Healthy Volunteers ,Respiratory Muscles ,030228 respiratory system ,chest expansion ,Cardiology ,Female ,business ,Body mass index ,Tape measure - Abstract
BACKGROUND: The purposes of this study were to verify the correlation between chest expansion and lung function within a larger sample of subjects composed of both healthy subjects and subjects affected by pulmonary disease, and to verify the influence of age, body mass index, and gender on chest expansion. METHODS: Adults were recruited prospectively when they visited the lung function lab. Chest expansion was measured with a measuring tape at 2 different levels of the rib cage by 1 blinded examiner. Spirometry was performed for each subject. RESULTS: Data from 251 subjects between 18 and 88 y old were collected and analyzed. Among the analyzed subjects, mean upper and lower chest expansion were 4.82 ± 1.84 cm and 3.99 ± 2.15 cm, respectively. A significant but poor correlation was found between both chest expansion and all lung function parameters (total lung capacity, FVC, and FEV1) (P = .01). Negative significant correlations were found between chest expansion and age as well as body mass index. The difference in upper chest expansion between obese and nonobese subjects was not statistically significant, but the difference in lower chest expansion was significant for these 2 groups. Finally, upper and lower chest expansion were not different between males and females. CONCLUSIONS: Based on these results, one cannot validate the use of chest expansion measurement to define lung function. In centers that have easy access to more precise and complete methods to measure lung function, the measurement of chest expansion for diagnostic purposes seems to be archaic. Additionally, age and body mass index are 2 parameters that can influence chest expansion.
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- 2020
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3. Reproducibility of the Sputum Color Evaluation Depends on the Category of Caregivers
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Giuseppe Liistro, Annie Robert, Laurence Couturiaux, Gregory Reychler, Thierry Pieters, Emmanuel André, K. Hohenwarter, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service de pneumologie, UCL - SSS/IREC/MBLG - Pôle de Microbiologie médicale, UCL - (SLuc) Service de microbiologie, and UCL - SSS/IREC/EPID - Pôle d'épidémiologie et biostatistique
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Adult ,Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Pediatrics ,Adolescent ,Respiratory Tract Diseases ,education ,Color ,Context (language use) ,Critical Care and Intensive Care Medicine ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Chart ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Aged ,Observer Variation ,Reproducibility ,COPD ,business.industry ,Sputum ,Reproducibility of Results ,Pulmonologist ,General Medicine ,Middle Aged ,medicine.disease ,Inter-rater reliability ,Pulmonology ,Caregivers ,030228 respiratory system ,Physical therapy ,Female ,Symptom Assessment ,medicine.symptom ,business - Abstract
BACKGROUND: Sputum production and purulence were proposed as criteria for justifying the use of antimicrobial agents. The Sputum Color Chart was developed and validated to standardize purulence of sputum evaluation. The aim of this study was to observe the reproducibility of the Sputum Color Chart from different categories of health caregivers. METHODS: The color of 10 sputum samples was evaluated using photographs for intra- and inter-reliability. The observation was repeated 3 times. Eighteen volunteers from 6 categories of health caregivers (student in physiotherapy, senior chest physiotherapist, junior resident in pulmonology, medical microbiologist, pulmonologist, and general practitioner) were investigated. // RESULTS: Poor inter-rater reliability was observed for all categories with the exception of senior chest physiotherapists. The best intra-rater reliability was observed for microbiologists and senior chest physiotherapists. We found a great proportion (>40%) of important discrepancies in 2 categories (junior pulmonologist and general practitioner). The proportion of non-discrepancy between evaluators varied between 10 and 40%, depending on the category. // CONCLUSIONS: Even if the Sputum Color Chart is a useful tool for the clinician in the context of clinical deterioration, it presents non-uniform reliability regarding the caregivers and their category.
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- 2016
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4. Influence of Ambient Music on Perceived Exertion During a Pulmonary Rehabilitation Session: A Randomized Crossover Study
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Emmanuelle Wasterlain, Gregory Reychler, Gilles Caty, Florian Mottart, Thierry Pieters, Maelle Boland, and Giuseppe Liistro
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Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Visual analogue scale ,medicine.medical_treatment ,Physical Exertion ,Anxiety ,Critical Care and Intensive Care Medicine ,Pulmonary Disease, Chronic Obstructive ,Physical medicine and rehabilitation ,medicine ,Humans ,Pulmonary rehabilitation ,Session (computer science) ,Fatigue ,Aged ,COPD ,Cross-Over Studies ,Exercise Tolerance ,business.industry ,Cardiorespiratory fitness ,General Medicine ,Middle Aged ,medicine.disease ,Crossover study ,humanities ,Exercise Therapy ,respiratory tract diseases ,Dyspnea ,Physical therapy ,Female ,Perception ,medicine.symptom ,business ,human activities ,Body mass index ,Music - Abstract
Pulmonary rehabilitation is a key element in the treatment of COPD. Music has been shown to have a positive effect on parameters related to a decrease in exercise tolerance. The aim of this study was to evaluate the effect of listening to ambient music on perceived exertion during a pulmonary rehabilitation session for COPD subjects.COPD subjects randomly performed a session of pulmonary rehabilitation with or without ambient music. Perceived exertion (Borg scales), anxiety (Hospital Anxiety and Depression Scale-Anxiety Subscale), dyspnea (visual analog scale), and cardiorespiratory parameters were compared at the end of both sessions.Forty-one subjects were analyzed. The characteristics of the COPD subjects were as follows: age, 70.5 ± 8.4 y; body mass index, 22.7 ± 3.9 kg/m(2); and FEV1, 38.6 ± 12.5 % predicted. Perceived exertion was not modified by ambient music, but anxiety was improved (P = .02). Dyspnea, fatigue and cardiorespiratory parameters were not influenced by music during a typical session of the pulmonary rehabilitation program.This study demonstrates that perceived exertion during one pulmonary rehabilitation session was not influenced by ambient music. However, a positive effect on anxiety was observed. (ClinicalTrials.gov registration NCT01833260.).
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- 2015
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5. Short-Term Effect of Autogenic Drainage on Ventilation Inhomogeneity in Adult Subjects With Stable Non-Cystic Fibrosis Bronchiectasis
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Nathalie Bauwens, Giuseppe Liistro, Anne-Sophie Aubriot, Gregory Reychler, William Poncin, Noémie Leeuwerck, Candice Nader, and Sophie Gohy
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Pulmonary and Respiratory Medicine ,Spirometry ,Adult ,Male ,Respiratory Therapy ,Vital Capacity ,Lung Clearance Index ,Critical Care and Intensive Care Medicine ,Pulmonary function testing ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Drainage, Postural ,medicine ,Humans ,Lung volumes ,030212 general & internal medicine ,Prospective Studies ,Airway clearance technique ,Lung ,Aged ,Aged, 80 and over ,Bronchiectasis ,medicine.diagnostic_test ,business.industry ,Sputum ,General Medicine ,Middle Aged ,medicine.disease ,Respiratory Function Tests ,Mucus ,Treatment Outcome ,030228 respiratory system ,Anesthesia ,Breathing ,Female ,medicine.symptom ,business ,Pulmonary Ventilation - Abstract
BACKGROUND: Lung clearance index (LCI), a measure of ventilation inhomogeneity derived from a multiple-breath washout test, is a promising tool for assessing airway function in patients with non-cystic fibrosis bronchiectasis. However, it is unknown whether ventilation inhomogeneity could improve after successful elimination of excessive secretions within bronchiectasis. The objective of this work was to assess the short-term effects of lung secretion clearance using the autogenic drainage technique on standard lung function tests and LCI in subjects with non-cystic fibrosis bronchiectasis. METHODS: Nitrogen-based multiple-breath washout, spirometry, and body plethysmography tests were performed 30 min before autogenic drainage in adults with stable non-cystic fibrosis bronchiectasis. The autogenic drainage session was followed by a 5-min break, after which the tests were repeated in the same order. Sputum expectorated during autogenic drainage was quantified as dry weight and correlated with change between post- and pre-measurements (Δ). Paired t test or Wilcoxon signed-rank tests were used to compare pre- and post-autogenic drainage measurement outcomes. A P value of ≤.05 was considered as statistically significant. RESULTS: Twenty-four subjects were studied (18 females, median age [range]: 65 [21–81] y). Mean ± SD LCI significantly improved after autogenic drainage (10.88 ± 2.62 vs 10.53 ± 2.35, P = .042). However, only 20% of subjects with mucus hyperproduction during autogenic drainage had a ΔLCI that exceeded measurement variability. The percent of predicted slow vital capacity (SVC%) also slightly improved (88.7 ± 19.3% vs 90 ± 19.1%, P = .02). ΔLCI was inversely related to dry sputum weight (r = −.48, P = .02) and ΔSVC% (r = −.64, P = .001). ΔSVC% also correlated with dry sputum weight (r = 0.46, P = .02). CONCLUSIONS: In adults with non-cystic fibrosis bronchiectasis and mucus hypersecretion, autogenic drainage improved ventilation inhomogeneity. LCI change may be the result of the maximum recruited lung volume and the amount of cleared mucus secretion. (ClinicalTrials.gov registration NCT02411981.)
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- 2017
6. Testing Spirometers: Are the Standard Curves of the American Thoracic Society Sufficient?
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Giuseppe Liistro, Quentin Lefebvre, Emilie Marchandise, Thomas Vandergoten, and Eric Derom
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Pulmonary and Respiratory Medicine ,Accuracy and precision ,medicine.medical_specialty ,business.industry ,Vital Capacity ,Reproducibility of Results ,Guidelines as Topic ,Peak Expiratory Flow Rate ,General Medicine ,Reference Standards ,Severe copd ,Critical Care and Intensive Care Medicine ,United States ,Pulmonary Disease, Chronic Obstructive ,Spirometry ,Forced Expiratory Volume ,Calibration ,Physical therapy ,Humans ,Medicine ,Computer Simulation ,business ,Societies, Medical ,Simulation ,Diagnostic Equipment - Abstract
BACKGROUND: The performance of spirometers is often measured only under ideal conditions, with a mechanical simulator reproducing the expiratory standard American Thoracic Society (ATS) curves generated by a computer. Studies have questioned the value of these results in real-life conditions. The aim of this study was to evaluate the accuracy and precision of 5 office spirometers with a flow-volume simulator using the ATS curves and using flow-volume curves obtained from patients. METHODS: We measured the FVC, peak expiratory flow, and FEV1 by simulating different dynamic waveforms applied by a computer-driven syringe, the Hans Rudolph flow-volume simulator. In addition to testing standard curves recommended by the ATS, we also tested curves obtained with subjects. RESULTS: The precision of the office spirometers was good and comparable using the standard ATS curves. One device presented the best performances in terms of accuracy and precision according to the ATS recommendations, but we observed significant biases in all devices with Bland-Altman analysis, particularly with the curves obtained from subjects with severe COPD. CONCLUSIONS: The global quality of most spirometers makes them acceptable for the detection of pulmonary diseases. However, we demonstrated accuracy issues not shown by the standard testing procedure. We propose to improve the testing of spirometers by implementing more realistic flow-volume curves and to refine the analysis of the results.
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- 2014
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7. Effect of Drug Targeting Nebulization on Lung Deposition: A Randomized Crossover Scintigraphic Comparison Between Central and Peripheral Delivery
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Anne-Sophie Aubriot, Gregory Reychler, Virginie Depoortere, François Jamar, and Giuseppe Liistro
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Adult ,Male ,Pulmonary and Respiratory Medicine ,Drug ,medicine.medical_specialty ,Lung deposition ,media_common.quotation_subject ,Urology ,Critical Care and Intensive Care Medicine ,Scintigraphy ,Drug Delivery Systems ,Double-Blind Method ,Administration, Inhalation ,Humans ,Medicine ,Gamma Cameras ,Radionuclide Imaging ,Lung ,media_common ,Aerosols ,Cross-Over Studies ,medicine.diagnostic_test ,business.industry ,Nebulizers and Vaporizers ,General Medicine ,Healthy Volunteers ,Peripheral ,Surgery ,Nebulizer ,medicine.anatomical_structure ,Targeted drug delivery ,Spirometry ,Technetium Tc 99m Pentetate ,Radiopharmaceuticals ,business ,Deposition (chemistry) - Abstract
Recent technological advances in nebulization permit researchers to target specific parts of the lungs by modifying delivery method. The aim of this study was to compare the central and peripheral targeted modalities of administration.Lung and regional deposition of inhaled technetium-99m diethylene triamine penta-acetic was measured by scintigraphy after peripheral and central targeted modalities of administration with an Akita device in 6 healthy subjects.Drug targeting nebulization delivered a large amount of drug into the peripheral part of the lung independent of the modality (outer-to-inner deposition ratio of 1.24 ± 0.21 vs. 1.22 ± 0.14 for central and peripheral modalities, respectively), but there was no difference in lung deposition (whole-body deposition, 83.3 ± 6.5% vs. 82.8 ± 7.3%, P = .86) or regional deposition (P = .77) between both modalities. The extrathoracic deposition was20% of the whole-body deposition, without a difference between modalities (P = .86).This study shows for the first time that choosing 2 different specific drug targeting nebulization modes does not influence the amount of drug delivered into the lung in healthy male subjects. Moreover, the modes do not modify the site of deposition under the conditions of our study.
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- 2014
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8. Technical Assessment of Spirometers Connected in Series
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Giuseppe Liistro, Thomas Vandergoten, Quentin Lefebvre, Emilie Marchandise, and Eric Derom
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Quality Control ,Pulmonary and Respiratory Medicine ,Equipment Safety ,Series (mathematics) ,business.industry ,Technical assessment ,Control engineering ,Equipment Design ,General Medicine ,Critical Care and Intensive Care Medicine ,Respiratory Function Tests ,law.invention ,Equipment Failure Analysis ,Spirometry ,law ,Safety Equipment ,Humans ,Medicine ,Lung Diseases, Obstructive ,business ,Spirometer - Abstract
Office spirometers are now widely used to detect obstructive lung diseases. To test the technical characteristics of these devices, simulation of different forced expiratory maneuvers is performed, using computer generated waveforms. However, the tests with human subjects are also useful to detect technical flaws. The procedure used by some authors to test the accuracy of office spirometers is to compare measurements made by 2 spirometers connected in series.The aim of this study was to evaluate the accuracy of this latter procedure.Two sets of 2 spirometers connected in series were used: the PocketSpiro with the MicroLoop, and the PocketSpiro with the SpiroScout. Different standard American Thoracic Society curves were selected for both ambient temperature and pressure (ATP) and body temperature and pressure saturated (BTPS) conditions and generated with a waveform simulator. We compared lung function indices (FVC, peak expiratory flow, and FEV(1)) recorded by the PocketSpiro when it was placed respectively upstream or downstream in the assembly.In ATP conditions, lung function indices were generally higher when the spirometer was placed downstream rather than upstream. The observed deviations reached up to 10%. In BTPS conditions, lung function indices were underestimated when the spirometer was placed downstream, as compared to the ATP procedure. The modification of the flow characteristics and the temperature drop are the 2 mechanisms that could explain our results.Connecting the spirometers in series gives variable results, depending on the position of the spirometer in the assembly. Individual tests are therefore essential, as results are not interchangeable.
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- 2012
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