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Start Over Author "Ono, Yoshinao" Journal respiratory investigation
4 results on '"Ono, Yoshinao"'

4. Increased LHX9expression in alveolar epithelial type 2 cells of patients with chronic obstructive pulmonary disease

Author

Okutomo, Koji, Fujino, Naoya, Yamada, Mitsuhiro, Saito, Takuya, Ono, Yoshinao, Okada, Yoshinori, Ichinose, Masakazu, and Sugiura, Hisatoshi

Abstract

Alveolar epithelial type 2 (AT2) cells serve as stem cells in alveolar epithelium and are assumed to lose their stem cell function in the lungs of chronic obstructive pulmonary disease (COPD). Although we previously reported that LHX9mRNA expression was up-regulated in AT2 cells of COPD lung tissues, it is yet to be elucidated how LHX9 is associated with the vulnerability of AT2 cells in COPD.

Published
2021
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