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Objective: Despite the full range of anti-epidemic measures, the rapidly mutating SARS-CoV-2 continues to spread worldwide, causing respiratory and pulmonary pathologies. So far, there are no generally accepted clinical guidelines for treating post-resuscitation cicatricial tracheal stenosis (CTS) after COVID-19 associated pneumonia. This study sought to evaluate the clinical outcomes of surgical treatment and perioperative management of patients who developed CTS., Methods: A cohort of eleven working-age patients (eight women and three men) with CTS were treated surgically after undergoing invasive artificial ventilation ranging from 5 to 130 days. Along with scarring changes in the tracheal wall, tracheomalacia was noted in five (55.6%) individuals. Circumferential tracheal resection (CTR) with subsequent anastomosis, tracheolaryngeal reconstruction, and endoscopic methods were modalities used to restore airway patency. In cases of CTR combined with tracheoesophageal fistula (TEF), CTR was performed with dissection of the pathological stoma., Results: In 80% of the cases, CTS was located at the larynx and cervical trachea level. All patients managed to restore adequate breathing through their natural airways with preserved vocal function. No lethal outcomes were observed in the post-op period. Patient outcomes after CTR were considered excellent in nine patients who continued an active lifestyle and went straight to work. One patient, after laryngotracheoplasty and tracheal stenting, is at the final stage of treatment., Conclusions: These patients are at high risk of developing CTS and require dynamic monitoring. CTR allows early rehabilitation of patients with the best functional outcome. If CTR is contraindicated, laryngotracheoplasty also allows adequate debridement of the tracheobronchial tree and respiratory support., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2022 The Authors.)

A case of the successful reconstruction of an extensive chest wall defect combined with a ventral hernia in a patient after multimodality treatment of breast cancer complicated by sternal and costal osteomyelitis is presented. To recover the chest mechanics, with emphasis on the supporting function, and to repair the hernial defect, customized reinforced "sandwich" TiNi rib endografts and knitted TiNi surgical mesh were used. A five-year follow-up indicated no recurrence of osteomyelitis or ventral hernia, and no failure/migration of the implants or instability of the thorax. Excellent clinical and functional outcomes were achieved pursuant to the Enneking score., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2021 The Authors.)