5 results on '"Lin, Xiaoping"'
Search Results
2. FERMT3 mediates cigarette smoke-induced epithelial–mesenchymal transition through Wnt/β-catenin signaling
- Author
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Su, Xiaoshan, Chen, Junjie, Lin, Xiaoping, Chen, Xiaoyang, Zhu, Zhixing, Wu, Weijing, Lin, Hai, Wang, Jianming, Ye, Xiangjia, and Zeng, Yiming
- Published
- 2021
- Full Text
- View/download PDF
3. Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients
- Author
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Zhao Changqing, Wu Jinzhun, Tan Guolin, Zhao Deyu, Lin Xiaoping, Huang Ying, Li Jing, Zhao Jing, Spangfort Michael D, and Zhong Nanshan
- Subjects
sensitization ,aeroallergens ,disease severity ,allergic rhinitis ,asthma ,association. ,Diseases of the respiratory system ,RC705-779 - Abstract
Abstract Background The association between sensitizations and severity of allergic diseases is controversial. Objective This study was to investigate the association between severity of asthma and rhinitis and degree of specific allergic sensitization in allergic patients in China. Method A cross-sectional survey was performed in 6304 patients with asthma and/or rhinitis from 4 regions of China. Patients completed a standardized questionnaire documenting their respiratory and allergic symptoms, their impact on sleep, daily activities, school and work. They also underwent skin prick tests with 13 common aeroallergens. Among the recruited subjects, 2268 provided blood samples for serum measurement of specific IgE (sIgE) against 16 common aeroallergens. Results Significantly higher percentage of patients with moderate-severe intermittent rhinitis were sensitized to outdoor allergens while percentage of patients sensitized to indoor allergens was increased with increasing severity of asthma. Moderate-severe intermittent rhinitis was associated with the skin wheal size and the level of sIgE to Artemisia vulgaris and Ambrosia artemisifolia (p < 0.001). Moderate-severe asthma was associated with increasing wheal size and sIgE response to Dermatophagoides (D.) pteronyssinus and D. farinae (p < 0.001). Moderate-severe rhinitis and asthma were also associated with increase in number of positive skin prick test and sIgE. Conclusions Artemisia vulgaris and Ambrosia artemisifolia sensitizations are associated with the severity of intermittent rhinitis and D. pteronyssinus and D. farinae sensitizations are associated with increasing severity of asthma in China. Increase in number of allergens the patients are sensitized to may also increase the severity of rhinitis and asthma.
- Published
- 2011
- Full Text
- View/download PDF
4. Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients.
- Author
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Jing Li, Ying Huang, Xiaoping Lin, Deyu Zhao, Guolin Tan, Jinzhun Wu, Changqing Zhao, Jing Zhao, Spangfort, Michael D., Nanshan Zhong, Li, Jing, Huang, Ying, Lin, Xiaoping, Zhao, Deyu, Tan, Guolin, Wu, Jinzhun, Zhao, Changqing, Zhao, Jing, Zhong, Nanshan, and China Alliance of Research on Respiratory Allergic Disease (CARRAD)
- Subjects
ASTHMA treatment ,RHINITIS ,ALLERGY treatment ,CROSS-sectional method ,QUESTIONNAIRES ,DERMATOPHAGOIDES ,DISEASE risk factors - Abstract
Background: The association between sensitizations and severity of allergic diseases is controversial.Objective: This study was to investigate the association between severity of asthma and rhinitis and degree of specific allergic sensitization in allergic patients in China.Method: A cross-sectional survey was performed in 6304 patients with asthma and/or rhinitis from 4 regions of China. Patients completed a standardized questionnaire documenting their respiratory and allergic symptoms, their impact on sleep, daily activities, school and work. They also underwent skin prick tests with 13 common aeroallergens. Among the recruited subjects, 2268 provided blood samples for serum measurement of specific IgE (sIgE) against 16 common aeroallergens.Results: Significantly higher percentage of patients with moderate-severe intermittent rhinitis were sensitized to outdoor allergens while percentage of patients sensitized to indoor allergens was increased with increasing severity of asthma. Moderate-severe intermittent rhinitis was associated with the skin wheal size and the level of sIgE to Artemisia vulgaris and Ambrosia artemisifolia (p < 0.001). Moderate-severe asthma was associated with increasing wheal size and sIgE response to Dermatophagoides (D.) pteronyssinus and D. farinae (p < 0.001). Moderate-severe rhinitis and asthma were also associated with increase in number of positive skin prick test and sIgE.Conclusions: Artemisia vulgaris and Ambrosia artemisifolia sensitizations are associated with the severity of intermittent rhinitis and D. pteronyssinus and D. farinae sensitizations are associated with increasing severity of asthma in China. Increase in number of allergens the patients are sensitized to may also increase the severity of rhinitis and asthma. [ABSTRACT FROM AUTHOR]- Published
- 2011
- Full Text
- View/download PDF
5. Influence of degree of specific allergic sensitivity on severity of rhinitis and asthma in Chinese allergic patients.
- Author
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Li J, Huang Y, Lin X, Zhao D, Tan G, Wu J, Zhao C, Zhao J, Spangfort MD, and Zhong N
- Subjects
- Adolescent, Adult, Aged, Asthma diagnosis, Asthma epidemiology, Chi-Square Distribution, Child, Child, Preschool, China epidemiology, Cross-Sectional Studies, Humans, Immunoglobulin E blood, Inhalation Exposure, Intradermal Tests, Logistic Models, Middle Aged, Odds Ratio, Rhinitis, Allergic, Perennial diagnosis, Rhinitis, Allergic, Perennial epidemiology, Rhinitis, Allergic, Seasonal diagnosis, Rhinitis, Allergic, Seasonal epidemiology, Severity of Illness Index, Surveys and Questionnaires, Young Adult, Allergens immunology, Asthma immunology, Rhinitis, Allergic, Perennial immunology, Rhinitis, Allergic, Seasonal immunology
- Abstract
Background: The association between sensitizations and severity of allergic diseases is controversial., Objective: This study was to investigate the association between severity of asthma and rhinitis and degree of specific allergic sensitization in allergic patients in China., Method: A cross-sectional survey was performed in 6304 patients with asthma and/or rhinitis from 4 regions of China. Patients completed a standardized questionnaire documenting their respiratory and allergic symptoms, their impact on sleep, daily activities, school and work. They also underwent skin prick tests with 13 common aeroallergens. Among the recruited subjects, 2268 provided blood samples for serum measurement of specific IgE (sIgE) against 16 common aeroallergens., Results: Significantly higher percentage of patients with moderate-severe intermittent rhinitis were sensitized to outdoor allergens while percentage of patients sensitized to indoor allergens was increased with increasing severity of asthma. Moderate-severe intermittent rhinitis was associated with the skin wheal size and the level of sIgE to Artemisia vulgaris and Ambrosia artemisifolia (p < 0.001). Moderate-severe asthma was associated with increasing wheal size and sIgE response to Dermatophagoides (D.) pteronyssinus and D. farinae (p < 0.001). Moderate-severe rhinitis and asthma were also associated with increase in number of positive skin prick test and sIgE., Conclusions: Artemisia vulgaris and Ambrosia artemisifolia sensitizations are associated with the severity of intermittent rhinitis and D. pteronyssinus and D. farinae sensitizations are associated with increasing severity of asthma in China. Increase in number of allergens the patients are sensitized to may also increase the severity of rhinitis and asthma.
- Published
- 2011
- Full Text
- View/download PDF
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