1. VITREORETINAL SURGERY FOR PATIENTS WITH SEVERE EXUDATIVE AND PROLIFERATIVE MANIFESTATIONS OF RETINAL CAPILLARY HEMANGIOBLASTOMA BECAUSE OF VON HIPPEL-LINDAU DISEASE
- Author
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Sami Yilmaz, Berkant Kaderli, Umit Ubeyt Inan, Sadik Gorkem Cevik, Remzi Avci, Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı., and Kaderli, Berkant
- Subjects
Male ,Visual acuity ,von Hippel-Lindau Disease ,genetic structures ,Visual Acuity ,Procedures ,Retina macula hole ,Retinal hemangioblastoma ,Capillary ,0302 clinical medicine ,Cancer surgery ,Silicone oil ,Occlusion ,Medicine ,Retinoblastoma ,Retinal detachment ,General Medicine ,Vitreoretinal surgery ,Middle Aged ,Hemangioblastoma ,Retrospective study ,Female ,medicine.symptom ,Hemangioma ,Human ,Von hippel lindau disease ,Adult ,medicine.medical_specialty ,Retina detachment ,Retina exudate ,Clinical article ,Retinal Neoplasms ,Retinal hemangioblastoma resection ,Vitreoretinal Surgery ,Article ,03 medical and health sciences ,Quadrant (abdomen) ,Disease association ,Ophthalmology ,Humans ,Von Hippel–Lindau disease ,Retrospective Studies ,Retinal Capillary Hemangioblastoma ,Rubeosis iridis ,Retinal capillary hemangioblastoma ,business.industry ,Von Hippel Lindau Disease ,Case Report ,Pars plana vitrectomy ,medicine.disease ,Resection ,Laser coagulation ,eye diseases ,Surgery ,Capillaries ,Young adult ,030221 ophthalmology & optometry ,Therapy ,business ,Vitreoretinopathy ,Complication ,030217 neurology & neurosurgery - Abstract
Purpose: The evaluation of long-term results of vitreoretinal surgery and retinal capillary hemangioblastoma (RCH) resection in patients with complicated retinal detachment (RD) secondary to RCHs. Methods: Twelve eyes of 12 patients were operated on with vitreoretinal surgery, including occlusion of afferent and efferent feeder vessels with endodiathermy and endolaser photocoagulation, and subsequent resection of RCHs. The long-term anatomical and visual outcomes were retrospectively evaluated. Results: Total exudative RD was detected in six eyes and subtotal exudative RD was found in the remaining six eyes. A tractional component was present in eight eyes, and four eyes had pure exudative RD. Laser treatment had been previously applied to four eyes but vitreoretinal surgery was the primary treatment in eight eyes. A total of 19 RCHs were resected. The quadrant location of RCHs was superior temporal in six, superior nasal in five, inferior nasal in five, and inferior temporal in three. The dimensions of the RCHs ranged between 1 and 4 disk diameters (DD) (1-DD in 1 eye, 1.5-DD in 3, 2-DD in 10, 2.5-DD in 3, 3-DD in 1, and 4-DD in 1). Preoperative mean logarithm of the minimum angle of resolution visual acuity was 1.9 +/- 1.0 (3.0-0.7) (20/1,588 +/- 20/200 [20/20,000-20/100]). Silicone oil and C3F8 was applied to four and eight eyes, respectively. The median postoperative follow-up was 30.5 (18-48) months. Single operation and final anatomical success was obtained in 9 and 11 eyes, respectively. Mean logarithm of the minimum angle of resolution visual acuity in the postoperative 18th month and at the final visit were 1.05 +/- 0.8 (3.0-0.2) (20/224 +/- 20/125 [20/20,000-20/32]) and 0.96 +/- 0.8 (3.0-0.2) (20/182 +/- 20/125 [20/20,000-20/32]), respectively. New RCHs occurred in eight eyes. Rubeosis iridis was not present in any of the eyes. Conclusion: Promising anatomical and visual outcomes were obtained after vitreoretinal surgery and resection of RCHs in eyes with complicated RD secondary to RCH. However, life-long follow-up is needed to recognize recurrent RD seen even in the early period or recurrences of RCHs seen in the long-term period.
- Published
- 2016