1. DEVELOPMENT OF PACHYCHOROID PIGMENT EPITHELIOPATHY AND TRANSFORMATION TO CENTRAL SEROUS CHORIORETINOPATHY AFTER INTRAVITREAL DEXAMETHASONE IMPLANTATION
- Author
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Murat Karacorlu, Serra Arf, Isil Sayman Muslubas, Mumin Hocaoglu, and Mehmet Giray Ersoz
- Subjects
medicine.medical_specialty ,Retinal pigment epithelium ,business.industry ,010102 general mathematics ,Diabetic macular edema ,General Medicine ,01 natural sciences ,eye diseases ,03 medical and health sciences ,Ophthalmology ,Pigment epithelial detachment ,Serous fluid ,0302 clinical medicine ,medicine.anatomical_structure ,030221 ophthalmology & optometry ,Medicine ,sense organs ,Choroid ,Implant ,0101 mathematics ,business ,Dexamethasone ,Cumulative effect ,medicine.drug - Abstract
Purpose To report first case of sequential development of pachychoroid pigment epitheliopathy (PPE) and central serous chorioretinopathy (CSC) after repeated intravitreal dexamethasone implantations for diabetic macular edema treatment. Methods We present a case of a 54-year-old man having intravitreal dexamethasone implant for bilateral diabetic macular edema. Results We observed development of pachychoroid pigment epitheliopathy, seen as a small pigment epithelial detachment on optical coherence tomography after a fourth dexamethasone implantation. A fifth implantation caused transformation of pachychoroid pigment epitheliopathy to central serous chorioretinopathy. Conclusion Consecutive administration of dexamethasone implants may have a cumulative effect on retinal pigment epithelium, Bruch membrane, and choroid.
- Published
- 2021
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