1. Thrombotic Manifestations in SAPHO Syndrome. Review of the Literature
- Author
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María Dolores Sánchez-González, Tatiana Elizabeth Carranco-Medina, Ricardo Usategui-Martín, Laura Pérez-Garrido, Olga Martínez-González, Alba Quesada-Moreno, Carlos Alberto Montilla-Morales, Cristina Hidalgo-Calleja, Ismael Calero-Paniagua, Javier del Pino-Montes, and Susana Gómez-Castro
- Subjects
Venous Thrombosis ,SAPHO syndrome ,medicine.medical_specialty ,Hyperostosis ,Vena Cava, Superior ,business.industry ,Acquired Hyperostosis Syndrome ,General Medicine ,Subclavian Vein ,medicine.disease ,Pustulosis ,Dermatology ,Thrombosis ,Venous thrombosis ,Risk Factors ,Synovitis ,medicine ,Humans ,Radiology ,Osteitis ,medicine.symptom ,business ,Subclavian vein - Abstract
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a cluster of osteo-cutaneous manifestations that can lead to serious complications such as thrombosis of the subclavian vein or superior vena cava, mainly in patients with significant inflammatory involvement of the anterior chest wall. The objective of this study was to review the cases published in the medical literature related with the presence of thrombotic complications in patients diagnosed with SAPHO syndrome and to try to determine their possible pathogenic mechanism and risk factors. We analyzed 11 published reports of isolated clinical cases or case series, a total of 144 patients, which described a total of 15 cases of venous thrombosis. The clinical characteristics of these patients, evaluated to determine whether they meet the ASAS criteria for axial and peripheral spondyloarthritis, are analyzed and the need for early diagnosis and treatment is highlighted.
- Published
- 2015
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