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Start Over Author "Alamo C" Journal revista clinica espanola
6 results on '"Alamo C"'

2. [Serial assessment of the nutritional status of patients infected by the human immunodeficiency virus. Role of tumor necrosis factor/its receptors]

Author

Segura Fernández E, Domenech Cienfuegos I, Pérez Guzmán E, Guerrero Sánchez F, Jc, Escribano Moriana, Pérez Cano R, Fernández-Gutiérrez del Alamo C, and José-Antonio Girón-González

Subjects
Adult, Male, Acquired Immunodeficiency Syndrome, Tumor Necrosis Factor-alpha, Humans, Nutritional Status, Female, Prospective Studies, Receptors, Tumor Necrosis Factor
Abstract

In order to analyze the nutritional status of HIV infected patients and the involvement of the tumour necrosis factor-alpha (TNF-alpha) and its soluble receptors (sTNFRI and sTNFRII) in such an status, forty HIV infected patients, with no associated systemic opportunist infections, were prospectively followed for eight months. From each patient the following were obtained: clinical history, dietetic survey, anthropometric measurements, CD4+ T lymphocyte/mm3 count, HIV load, and serum concentration of TNF and sTNFRI and sTNFRII. Patients showed a nutritional disorder which involved mainly the fat compartment (mean tricipital skin fold 9.8 +/- 4.2 mm, that is, 65.7 +/- 27.4% of the ideal fold), associated with a hypocaloric intake (mean daily intake 1,659.5 +/- 543.0 kcal), with normal proportions of the different organic principles. Serum concentrations of TNF (87.9 +/- 79.2 vs 8.7 +/- 6.1 pg/ml, p = 0.048) and its receptors, sTNFRI (6.1 +/- 2.6 vs 1.0 +/- 0.8 pg/ml, p0.001) and sTNFRII (41.9 +/- 18.6 vs 6.3 +/- 3.6 pg/ml, p0.001) were significantly higher than those detected in a sample of ten healthy controls. No correlation was found between nutritional alterations and concentrations of TNF or its receptors, viral load, and counts of CD4+ T lymphocytes/mm3. Seventeen patients completed the follow-up period. During this period, no significant modifications in the analyzed parameters were observed: tricipital skin fold, arm circumference, serum concentrations of albumin or transferrin, concentrations of tumoral necrosis factor or its receptor and caloric intake. The conclusion is that, despite the detected nutritional alterations in the nutritional status and those in the TNF/receptor system, our data no support and interrelationship between them.

Published
2000

3. [Serial assessment of the nutritional status of patients infected by the human immunodeficiency virus. Role of tumor necrosis factor/its receptors].

Author

Segura Fernández E, Domenech Cienfuegos I, Pérez Guzmán E, Guerrero Sánchez F, Escribano Moriana JC, Pérez Cano R, Fernández-Gutiérrez del Alamo C, and Girón González JA

Subjects
Adult, Female, Humans, Male, Prospective Studies, Acquired Immunodeficiency Syndrome blood, Nutritional Status, Receptors, Tumor Necrosis Factor blood, Tumor Necrosis Factor-alpha analysis
Abstract

In order to analyze the nutritional status of HIV infected patients and the involvement of the tumour necrosis factor-alpha (TNF-alpha) and its soluble receptors (sTNFRI and sTNFRII) in such an status, forty HIV infected patients, with no associated systemic opportunist infections, were prospectively followed for eight months. From each patient the following were obtained: clinical history, dietetic survey, anthropometric measurements, CD4+ T lymphocyte/mm3 count, HIV load, and serum concentration of TNF and sTNFRI and sTNFRII. Patients showed a nutritional disorder which involved mainly the fat compartment (mean tricipital skin fold 9.8 +/- 4.2 mm, that is, 65.7 +/- 27.4% of the ideal fold), associated with a hypocaloric intake (mean daily intake 1,659.5 +/- 543.0 kcal), with normal proportions of the different organic principles. Serum concentrations of TNF (87.9 +/- 79.2 vs 8.7 +/- 6.1 pg/ml, p = 0.048) and its receptors, sTNFRI (6.1 +/- 2.6 vs 1.0 +/- 0.8 pg/ml, p < 0.001) and sTNFRII (41.9 +/- 18.6 vs 6.3 +/- 3.6 pg/ml, p < 0.001) were significantly higher than those detected in a sample of ten healthy controls. No correlation was found between nutritional alterations and concentrations of TNF or its receptors, viral load, and counts of CD4+ T lymphocytes/mm3. Seventeen patients completed the follow-up period. During this period, no significant modifications in the analyzed parameters were observed: tricipital skin fold, arm circumference, serum concentrations of albumin or transferrin, concentrations of tumoral necrosis factor or its receptor and caloric intake. The conclusion is that, despite the detected nutritional alterations in the nutritional status and those in the TNF/receptor system, our data no support and interrelationship between them.

Published
1999

5. [Antidepressive agents: classification and mechanism of action].

Author

Cuenca E, Alamo C, and Coullaut-Jáuregui J

Subjects
Animals, Antidepressive Agents, Tricyclic classification, Antidepressive Agents, Tricyclic pharmacology, Brain drug effects, Dopamine Antagonists pharmacology, Electroshock, Humans, Monoamine Oxidase Inhibitors pharmacology, Norepinephrine antagonists & inhibitors, Receptors, Adrenergic drug effects, Receptors, Catecholamine drug effects, Receptors, Cholinergic drug effects, Receptors, Dopamine drug effects, Receptors, GABA drug effects, Receptors, Glucocorticoid drug effects, Receptors, Muscarinic drug effects, Receptors, Neurotransmitter drug effects, Receptors, Serotonin drug effects, Serotonin Antagonists pharmacology, Antidepressive Agents classification, Antidepressive Agents pharmacology
Published
1997

6. [Nocardiosis in a patient with AIDS].

Author

Marín Casanova P, García Martos P, Fernández Gutiérrez del Alamo C, García Herruzo J, Escribano Moriana JC, and Aznar Martín A

Subjects
Adult, Humans, Male, Acquired Immunodeficiency Syndrome complications, Nocardia Infections complications, Nocardia asteroides
Abstract

A young drug addict with positive anti-HIV antibodies, OKT4/OKT8 ratio below 1, oropharingeal candidiasis and pulmonary Pneumocystis carinii infection, dies due to a cerebral abscess with a septic status. The postmortem microbiologic study shows pulmonary abscesses and Nocardia asteroides is isolated from lung tissue and spinal fluid. We note out the rareness of this pathology and its relation to AIDS.

Published
1991

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