It is now recognized that the construction sector is one of the main generators of Construction and Demolition Waste (CDW) and emissions of greenhouse gases (GHG) worldwide. While nationally there is Resolution 0472 of 2017 to carry out proper management of the CDW, it is important to analyze the influence of compliance with this standard in the generation and GHG possible reduction nationwide. For this reason, the present research aims to technically assess the relationship between policy management component RCD (Resolution 472, 2017) and reducing the carbon footprint in the first phase of the construction cycle, setting a case study one high-rise building located in the Medellin city. Four scenarios of compliance with Programa de Manejo Ambiental (PMA) were proposed based on different concrete mix designs of compressive strength 24 MPa, also evaluating the carbon footprint of each scenario. Concrete mix designs presented the inclusion of superplasticizer admixtures, partial substitutions of cement for fly ash and / or partial substitutions of virgin aggregates for recycled aggregates. The results showed that in order to comply with the CDW regulations, the partial replacement of virgin aggregates with recycled aggregates is strategic (scenario 3), but for the reduction in the carbon footprint, the partial replacement of cement with fly ash, including superplasticizer admixtures, is important (scenario 2). Therefore, the stage 4 which links all the above strategies has high percentages of compliance (17.2% versus 11.3% in the baseline scenario) and a reduction in carbon footprint (338.1 kg CO2/m² versus 438.1 kg CO2/m² in the baseline scenario). [ABSTRACT FROM AUTHOR]