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Start Over Author "Jasmina Trifunovic Cvetkovic" Journal rheumatology
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1. Increased levels of autoantibodies against copper-oxidized low density lipoprotein, malondialdehyde-modified low density lipoprotein and cardiolipin in patients with rheumatoid arthritis

Author

Jasmina Trifunovic Cvetkovic, E Ahmed, Ann Kari Lefvert, Solbritt Rantapää-Dahlqvist, and Solveig Wållberg-Jonsson

Subjects
Male, medicine.medical_specialty, Cardiolipins, Immunoglobulins, Enzyme-Linked Immunosorbent Assay, medicine.disease_cause, Autoimmunity, Arthritis, Rheumatoid, chemistry.chemical_compound, Rheumatology, Malondialdehyde, Immunopathology, Internal medicine, Cardiolipin, Humans, Medicine, Pharmacology (medical), Autoantibodies, Autoimmune disease, biology, business.industry, Autoantibody, Middle Aged, medicine.disease, Lipoproteins, LDL, Endocrinology, chemistry, Cardiovascular Diseases, Low-density lipoprotein, Rheumatoid arthritis, Immunology, biology.protein, Female, lipids (amino acids, peptides, and proteins), Antibody, business, Oxidation-Reduction, Copper
Abstract

Objectives. To analyse the association of autoantibodies against cardiolipin (CL) and oxidized low density lipoproteins [copper-oxidized low density lipoprotein (oxLDL), malondialdehyde-modified LDL (MDA-LDL)] with rheumatoid arthritis (RA) and cardiovascular complications. Methods. One hundred and twenty-one patients with RA were consecutively included. Autoantibodies were determined by ELISA. Healthy individuals from the same region were used as controls. Results. Levels of IgG, IgM and IgA antibodies against MDA-LDL and CL, as well as IgG and IgA antibodies against oxLDL were increased in the patients (P

Published
2002

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