1. ANCA-associated vasculitis following ChAdOx1 nCoV19 vaccination: case-based review.
- Author
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Prabhahar, Arun, Naidu, G. S. R. S. N. K., Chauhan, Prabhat, Sekar, Aravind, Sharma, Aman, Sharma, Alok, Kumar, Asheesh, Nada, Ritambhra, Rathi, Manish, Kohli, Harbir Singh, and Ramachandran, Raja
- Subjects
COVID-19 ,ANTINEUTROPHIL cytoplasmic antibodies ,VACCINATION ,VASCULITIS ,DISEASE incidence ,AUTOIMMUNE diseases ,LEUKOCYTOCLASTIC vasculitis - Abstract
For the foreseeable future, vaccines are the cornerstone in the global campaign against the Coronavirus Disease-19 (COVID-19) pandemic. As the number and fatalities due to COVID-19 decline and the lockdown anywise rescinded, we recognize an increase in the incidence of autoimmune disease post-COVID-19 vaccination. However, the causality of the most vaccine-induced side effects is debatable and, at best, limited to a temporal correlation. We herein report a case of a 51-year-old gentleman who developed Anti-Neutrophil Cytoplasmic Antibody (ANCA)-associated vasculitis (AAV) 2 week post-COVID-19 vaccination. The patient responded favorably to oral steroids and rituximab. Additionally, we conducted a case-based review of vaccine-associated AAV describing their clinical manifestations and treatment response of this emerging entity. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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