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Your search keyword '"Elena-Cecilia Rosca"' showing total 4 results
Start Over Author "Elena-Cecilia Rosca" Journal romanian journal of neurology
4 results on '"Elena-Cecilia Rosca"'

1. Myoclonus as an unusual presentation of progressive multifocal leukoencephalopathy in a HIV positive patient

Author

Lucian Chicea, Elena Cecilia Rosca, Ovidiu Rosca, M. Ciolan, and Mihaela Simu

Subjects
myoclonus, progressive multifocal leukoencephalopathy, hiv, Medicine, Neurology. Diseases of the nervous system, RC346-429
Abstract

From mild muscular contractions to gross jerks affecting the whole body, myoclonus is an involuntary movement caused by an excessive discharge from a group of neurons located in one or multiple sites from cortical to peripheral level. Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease of the CNS caused by oligodendroglial destruction due to JC virus. Usually it manifests with focal neurological deficits such as motor weakness, sensory abnormalities, visual disturbances, cognitive impairments, movement disorders having a low incidence in these patients. We report a rare case of myoclonus as a neurological complication of PML in AIDS, analyzing the link between the stage of HIV infection, the MRI lesions and the type of myoclonus, being also aware of potential interactions between the antiepileptic drugs and the antiretroviral therapy.

Published
2012
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2. PATHOGENIC MECHANISMS OF HIV-1 ENCEPHALITIS

Author

Mihaela Simu, Elena-Cecilia Rosca, and Ruxandra Dana Chirileanu

Subjects
viruses, encephalitis, fungi, lcsh:R, pathogeny, virus diseases, food and beverages, lcsh:Medicine, hiv-1, lcsh:Neurology. Diseases of the nervous system, lcsh:RC346-429
Abstract

Human immunodeficiency virus type 1 (HIV-1) is a member of Lentivirus genus of retroviruses that can determine a relatively slow encephalitis. The pathogenesis of HIV-1 encephalitis (HIVE) can be discussed in terms of neuroinvasion, neurotropism and neurovirulence. Several mechanisms are implicated in the pathogenesis, some of them being still under investigation.

Published
2007

3. ANTERIOR SPINAL ARTERY INFARCT

Author

Mihaela Simu, T. Puscasiu, Elena-Cecilia Rosca, Ervin Herman, and Cornelia Duse

Subjects
lcsh:R, cardiovascular system, lcsh:Medicine, cardiovascular diseases, infarct, anterior spinal artery, lcsh:Neurology. Diseases of the nervous system, lcsh:RC346-429
Abstract

The infarcts of the spinal cord are a relatively rare disease, being described in small series of cases or case reports. We describe a case of a 51 year old female with a partial form of anterior spinal artery infarct presenting only brachial diplegia, with MRI scan showing a medullar infarct in the anterior spinal cord, from C3 to T1.

Published
2008

4. HERPES SIMPLEX ENCEPHALITIS

Author

Mihaela Simu, Elena-Cecilia Rosca, and T. Puscasiu

Subjects
encephalitis, lcsh:R, lcsh:Medicine, herpes simplex, lcsh:Neurology. Diseases of the nervous system, lcsh:RC346-429
Abstract

Herpes simplex encephalitis (HSE) is a serious disease, with increased risk of morbidity and mortality. We present the case of a 55 years old male who was admitted in our clinic with the suspicion of encephalitis with a MRI scan highly suggestive for HSE.

Published
2007

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